GATE: A Geant4-based simulation platform for PET and SPECT integrating movement and time management
GATE: A Geant4-based simulation platform for PET and SPECT integrating movement and time management
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DOI：
10.1109/tns.2003.817974
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发表时间：
2003-10-01
影响因子：
1.8
通讯作者：
Morel, C
中科院分区：
文献类型：
--
作者：
Santin, G;Strul, D;Morel, C
GATE是Geant4用于层析发射的应用程序，是为PET和SPECT开发的模拟平台。它结合了强大的模拟核心Geant4工具包和新开发的专门用于核医学的软件组件。特别是，它对实际捕获过程中的时间流逝进行建模，使其能够处理动态系统，如衰减源分布或移动探测器。我们提供了几个系列的结果来说明这个新平台的可能性。对衰减源的模拟是以多时间框架的双同位素采集为例的。对于双晶装置和小动物PET扫描仪配置，显示了考虑随机重合和死区时间的计数率曲线。显示了旋转PET扫描仪的模拟分辨率曲线和重建图像。最后，我们给出了模拟的点扩散函数和频谱与从小动物伽马相机原型上获得的实验结果的第一次比较。
GATE, the Geant4 application for tomographic emission, is a simulation platform developed for PET and SPECT. It combines a powerful simulation core, the Geant4 toolkit, with newly developed software components dedicated to nuclear medicine. In particular, it models the passing of time during real acquisitions, allowing it to handle dynamic systems such as decaying source distributions or moving detectors. We present several series of results that illustrate the possibilities of this new platform. The simulation of decaying sources is illustrated on a dual-isotope acquisition with multiple time-frames. Count rate curves taking into account random coincidences and dead-time are shown for a dual-crystal setup and for a small-animal PET scanner configuration. Simulated resolution curves and reconstructed images are shown for rotating PET scanners. Lastly, we present first comparisons of simulated point-spread functions and spectra with experimental results obtained from a small-animal gamma camera prototype.