Out-of-hospital cardiac arrest-the relevance of heart failure. The Maastricht Circulatory Arrest Registry
Out-of-hospital cardiac arrest-the relevance of heart failure. The Maastricht Circulatory Arrest Registry
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DOI：
10.1016/s0195-668x(03)00191-x
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发表时间：
2003-07-01
影响因子：
39.3
通讯作者：
Wellens, HJJ
中科院分区：
文献类型：
--
作者：
Gorgels, APM;Gijsbers, C;Wellens, HJJ
目的了解荷兰马斯特里赫特地区院外循环骤停（SCA）患者心力衰竭的发生率和病因。方法对1997年1月1日至2000年12月31日期间所有年龄在20 ~ 75岁的SCA病例进行分析。对心力衰竭的人口学特征、病因学及临床特征进行研究。结果纳入492例患者（72%为男性），平均年龄62±10岁。年SCA发病率为9.2/ 10000。在同一时期发生的猝死占所有死亡的19%。在52%的男性和59%的女性中，SCA是心脏病的第一个表现。在有心脏病史的SCA组中，26%的病例存在明显的心力衰竭，首次心力衰竭发作和SCA之间的时间间隔为4.3+/-6.3年。在心力衰竭组中，大多数患者先前处于较差的功能等级和LVEF。在病因学方面，在SCA组中，77%已知患有CAD， 72%已知患有旧发心肌梗死。在LVEF组中，50%的CAD是最常见的原因。结论：泵功能较差的SCA患者发生SCA的风险增加，大多数既往心力衰竭的SCA患者属于功能差级SCA。然而，心力衰竭仅见于SCA人群的少数。CAD是目前为止SCA最常见的病因。(C) 2003欧洲心脏病学会。Elsevier Ltd.出版。版权所有。
Aims To describe the incidence and aetiology of heart failure in out-of-hospital sudden circulatory arrest (SCA) in the Maastricht area of the Netherlands.Methods All cases of SCA were studied in the age group 20 to 75 years between 1 January 1997 and 31 December 2000. Demographic characteristics, aetiology and clinical features, related to heart failure were studied.Results Four hundred and ninety-two patients were included (72% men), mean age of 62+/-10. The yearly incidence of SCA was 9.2/10 000 inhabitants. Sudden death represented 19% of all deaths, occurring in the same time period. In 52% of the men and 59% of women, SCA was the first manifestation of heart disease. In the SCA group with a cardiac history overt heart failure was present in 26% of the cases, the time interval between the first heart failure episode and SCA being 4.3+/-6.3 year. In the heart failure group the majority had previously been in a poor functional class and LVEF. Concerning aetiotogy, of the SCA group, 77% were known with CAD and 72% with an old MI. Also in the group with a LVEF >50% CAD was the most frequent cause.Conclusions There is an increased risk of SCA at poorer pump function and most SCA victims with previous heart failure are in a poor functional class SCA. However heart failure is seen in only a minority of the SCA population. CAD is by far the most common cause of SCA. (C) 2003 The European Society of Cardiology. Published by Elsevier Ltd. All rights reserved.