Mechanisms of Working Memory Disruption by External Interference
Mechanisms of Working Memory Disruption by External Interference
复制标题
DOI：
10.1093/cercor/bhp150
复制
发表时间：
2010-04-01
期刊：
影响因子：
3.7
通讯作者：
Gazzaley, Adam
中科院分区：
文献类型：
--
作者：
Clapp, Wesley C.;Rubens, Michael T.;Gazzaley, Adam
外部干扰对工作记忆（WM）表现的负面影响是有据可查的，然而，这种破坏的机制还没有得到充分的理解。在这项研究中，脑电图和功能性磁共振成像（fMRI）数据被记录在单独的实验中，每个实验在WM维持期间引入不同类型的视觉干扰：分心（不相关的刺激）和中断（需要注意的刺激）。数据收敛显示，无论干扰的类型，在视觉皮层（快速为100毫秒）的处理干扰刺激的幅度预测随后的WM识别准确性存储的项目。功能磁共振成像连接分析表明，在分心的存在下，编码的项目保持在整个延迟期间通过额中回和视觉关联皮层之间的连接，而记忆没有保持时，受试者被中断，而是重新激活在postinterruption期间。这些结果阐明了外部干扰对工作记忆表现的影响机制，并强调了分心和多任务处理的异同。
The negative impact of external interference on working memory (WM) performance is well documented; yet, the mechanisms underlying this disruption are not sufficiently understood. In this study, electroencephalogram and functional magnetic resonance imaging (fMRI) data were recorded in separate experiments that each introduced different types of visual interference during a period of WM maintenance: distraction (irrelevant stimuli) and interruption (stimuli that required attention). The data converged to reveal that regardless of the type of interference, the magnitude of processing interfering stimuli in the visual cortex (as rapidly as 100 ms) predicted subsequent WM recognition accuracy for stored items. fMRI connectivity analyses suggested that in the presence of distraction, encoded items were maintained throughout the delay period via connectivity between the middle frontal gyrus and visual association cortex, whereas memoranda were not maintained when subjects were interrupted but rather reactivated in the postinterruption period. These results elucidate the mechanisms of external interference on WM performance and highlight similarities and differences of distraction and multitasking.