Light damage in the developing rat retina.
Light damage in the developing rat retina.
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正在发育的大鼠视网膜受到光损伤。
DOI：
10.1001/archopht.1976.03910040237017
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发表时间：
1976
影响因子：
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通讯作者：
M. Funahashi
中科院分区：
文献类型：
--
作者：
T. Kuwabara;M. Funahashi
电镜观察了强光对发育中的白化病大鼠视网膜的影响。与在正常光照条件下饲养至少两周的新生大鼠相比，在持续强光下饲养的新生大鼠新形成的外段片层膜对光线的破坏性影响似乎不那么敏感。持续暴露在荧光灯下大约需要两天的时间，膜才会出现损伤。同样的亮度会在几小时内破坏成虫的外层。尽管外部部分严重受损，视网膜的其余部分在一个月内正常发育，然后感光细胞发生变性。出生后暴露在明亮光线下两周的视网膜会受到相当大的损伤，但这些视网膜会在六个月内再生。
The effect of bright light on the retinas of developing albino rats was studied electron microscopically. The newly formed outer-segment lamellar membranes of newborn rats raised in continuous bright light appear to be less sensitive to the damaging effects of light, compared to those of rats raised under normal light conditions for at least two weeks. It seems to take about two days before the membranes show damage from continuous exposure to fluorescent lamps. The same brightness damages the adult outer segments within a few hours. Despite the severe damage to the outer segments, the rest of the retina develops normally for one month, and then the photoreceptor cells undergo degeneration. The retinas that have been exposed to bright light for two weeks after birth show considerable damage, but these retinas regenerate in six months.