B and C floral organ identity functions require SEPALLATA MADS-box genes
B and C floral organ identity functions require SEPALLATA MADS-box genes
复制标题
DOI：
10.1038/35012103
复制
发表时间：
2000-05-11
期刊：
影响因子：
64.8
通讯作者：
Yanofsky, MF
中科院分区：
文献类型：
--
作者：
Pelaz, S;Ditta, GS;Yanofsky, MF
人们认识异常花朵已有数千年的历史，但直到最近十年，花朵发育的奥秘才开始揭开。在这些谜团中，有四种不同的器官类型（萼片、花瓣、雄蕊和心皮）的分化，每一种都可能是一片变异的叶（1）。植物发育生物学的一个里程碑式的成就是花器官身份的ABC模型（2，3）。这个简单的模型提供了一个概念框架，解释ABC基因的单独和组合活动如何产生典型真双子叶植物花的四种器官类型。在这里，我们表明，活动的B和C器官的身份基因需要三个密切相关的和功能冗余的MADS盒基因，SEPALLATA 1/2/3（SEP 1/2/3）的活动。缺乏所有三个SEP基因活性的三重突变拟南芥植物产生所有器官发育为萼片的花。因此SEP 1/2/3是花瓣、雄蕊和心皮发育所需的一类器官识别基因。
Abnormal flowers have been recognized for thousands of years, but only in the past decade have the mysteries of flower development begun to unfold. Among these mysteries is the differentiation of four distinct organ types (sepals, petals, stamens and carpels), each of which may be a modified leaf(1). A landmark accomplishment in plant developmental biology is the ABC model of flower organ identity(2,3). This simple model provides a conceptual framework for explaining how the individual and combined activities of the ABC genes produce the four organ types of the typical eudicot flower. Here we show that the activities of the B and C organ-identity genes require the activities of three closely related and functionally redundant MADS-box genes, SEPALLATA1/2/3 (SEP1/2/3). Triple mutant Arabidopsis plants lacking the activity of all three SEP genes produce flowers in which all organs develop as sepals. Thus SEP1/2/3 are a class of organ-identity genes that is required for development of petals, stamens and carpels.