National Breakthrough Pain Study: prevalence, characteristics, and associations with health outcomes
National Breakthrough Pain Study: prevalence, characteristics, and associations with health outcomes
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DOI：
10.1097/01.j.pain.0000460305.41078.7d
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发表时间：
2015-02-01
期刊：
影响因子：
7.4
通讯作者：
Portenoy, Russell K.
中科院分区：
文献类型：
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作者：
Narayana, Arvind;Katz, Nathaniel;Portenoy, Russell K.
国家突破性疼痛研究是一项大型观察性研究，评估了阿片类药物治疗慢性疼痛的商业保险社区居民患者人群的突破性疼痛（BTP）。从行政索赔数据库中确定符合条件的患者，并要求同意的患者完成结构化电话访谈和几份经验证的问卷。问卷评估了疼痛对功能（简明疼痛量表-简表）、健康状况（简表12 [SF-12]健康调查）、残疾（希恩残疾量表）、工作表现（世界卫生组织健康和工作表现问卷）和情绪（广泛性焦虑症-7筛选器[GAD-7]和患者健康问卷-2 [PHQ-2]）的干扰。在接受采访的2198例患者中，1278例患者接受阿片类药物治疗控制了持续性疼痛;其中1023例（80%）患者报告了BTP。患者每天BTP发作的中位数为2.0次（范围1-50），BTP的中位数持续时间为45分钟（范围1-720）。与无BTP的患者相比，BTP患者的疼痛相关功能干扰更多（简明疼痛量表，平均SD：34.2 ± 15.6 vs 25.0 ± 15.7 [P
The National Breakthrough Pain Study is a large observational study that assessed breakthrough pain (BTP) in a population of commercially insured community-dwelling patients with opioid-treated chronic pain. Eligible patients were identified from an administrative claims database, and consenting patients were asked to complete a structured telephone interview and several validated questionnaires. Questionnaires assessed pain interference with function (Brief Pain Inventory-Short Form), health status (Short Form 12 [SF-12] Health Survey), disability (Sheehan Disability Scale), work performance World Health Organization Health and Work Performance Questionnaire), and mood (Generalized Anxiety Disorder-7 Screener [GAD-7] and-Patient Health Questionnaire-2 [PHQ-2]). Of 2198 patients interviewed, 1278 patients had persistent pain controlled with opioid therapy; 1023 (80%) of these patients reported BTP. Patients had a median of 2.0 episodes of BTP per day (range, 1-50) and a median duration of BTP of 45 minutes (range, 1-720). Compared with patients without BTP, patients with BTP had more pain-related interference in function (Brief Pain Inventory, mean SD: 34.2 +/- 15.6 vs 25.0 +/- 15.7 [P