Multiple Pilus Motors Cooperate for Persistent Bacterial Movement in Two Dimensions
Multiple Pilus Motors Cooperate for Persistent Bacterial Movement in Two Dimensions
复制标题
DOI：
10.1103/physrevlett.104.178104
复制
发表时间：
2010-04-30
影响因子：
8.6
通讯作者：
Maier, Berenike
中科院分区：
文献类型：
--
作者：
Holz, Claudia;Opitz, Dirk;Maier, Berenike
在各种细菌物种的表面运动是介导的IV型菌毛电机延长，粘附和回缩的周期，但目前还不清楚细菌运动是否遵循随机行走。在这里，我们表明，淋病奈瑟菌的持续运动的相关时间增加的皮利的数量。单个皮利从表面F = 10 pN的解束缚力显著低于失速力F > 100 pN，这表明菌毛马达的密度、力和粘附特性使得细菌运动的拔河机制成为可能。
In various bacterial species surface motility is mediated by cycles of type IV pilus motor elongation, adhesion, and retraction, but it is unclear whether bacterial movement follows a random walk. Here we show that the correlation time of persistent movement in Neisseria gonorrhoeae increases with the number of pili. The unbinding force of individual pili from the surface F = 10 pN was considerably lower than the stalling force F > 100 pN, suggesting that density, force, and adhesive properties of the pilus motor enable a tug-of-war mechanism for bacterial movement.