Current-voltage relationship of the basolateral membrane of a tight epithelium.
Current-voltage relationship of the basolateral membrane of a tight epithelium.
复制标题
紧密上皮基底外侧膜的电流-电压关系。
DOI:
10.1016/0005-2736(79)90405-x
复制
发表时间:
1979
期刊:
影响因子:
--
通讯作者:
M. S. Ifshin
中科院分区:
文献类型:
--
作者:
N. Wills;D. Eaton;S. Lewis;M. S. Ifshin
The polyene antibiotic nystatin is used to reduce selectively to zero the apical membrane resistance of the rabbit descending colon, allowing the measurement of the current-voltage curve of the basolateral membrane. TheI—Vrelationship is described by the Goldman-Hodgkin-Katz equations allowing calculation ofPNa/PK,PCl/PKandPKfor the basolateral membrane. Cs+is found to block inward current (serosa → mucosa) in a manner similar to that found in excitable membranes.