Endoscopic Resection of Sinonasal Malignancies
Endoscopic Resection of Sinonasal Malignancies
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DOI：
10.1007/s11912-011-0151-6
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发表时间：
2011-04-01
影响因子：
4.7
通讯作者：
Villaret, Andrea Bolzoni
中科院分区：
文献类型：
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作者：
Nicolai, Piero;Castelnuovo, Paolo;Villaret, Andrea Bolzoni
鼻窦恶性肿瘤是罕见的，仅占所有恶性肿瘤的1%。虽然它们与大量的组织学异质性有关，但手术在其管理中起着关键作用。本文综述了内窥镜切除技术的引入对目前治疗方法的演变。与传统的外部方法相比，内窥镜技术的主要优点是没有面部切口和截骨术，缩短住院时间，更好地控制出血，改善肿瘤边界的可视化，降低发病率和死亡率。主要的批评集中在肿瘤学结果上，因为大系列的短期/中期随访通常将可能与不同肿瘤相关的几种组织学分组在一起。由于内窥镜和颅面切除术的结果对比的前瞻性研究是难以进行的疾病的罕见性和伦理问题，创建一个大型数据库将有利于分析与患者，肿瘤，并对大量患者的生存治疗的几个变量。
Malignant tumors of the sinonasal tract are rare, accounting for only 1% of all malignancies. Although they are associated with substantial histological heterogeneity, surgery plays a key role in their management. This review addresses the evolution of current treatments in view of the introduction of endoscopic resection techniques. The absence of facial incisions and osteotomies, decreased hospitalization time, better control of bleeding, improved visualization of tumor borders, and reduced morbidity and mortality rate are the major advantages of endoscopic techniques in comparison to traditional external approaches. The major criticisms focus on oncologic results in view of the short/intermediate follow-up of large series, which have commonly grouped together several histologies that may be associated with different prognoses. Since prospective studies contrasting the results of endoscopic and craniofacial resections are difficult to carry out given the rarity of the disease together with ethical issues, the creation of a large database would favor the analysis of several variables related to the patient, tumor, and treatment on survival performed on a large number of patients.