HMPA-free generation of trialkylsilyllithium reagents and its application to the synthesis of silylboronic esters.
HMPA-free generation of trialkylsilyllithium reagents and its application to the synthesis of silylboronic esters.
复制标题
无HMPA生成三烷基甲硅烷基锂试剂及其在甲硅烷基硼酸酯合成中的应用。
DOI：
10.1055/s-0040-1706285
复制
发表时间：
2021
期刊：
影响因子：
--
通讯作者：
M.; Yoshida
中科院分区：
文献类型：
--
作者：
Kamio;S.; Imagawa;T.; Nakamoto;M.; Oestreich;M.; Yoshida
三烷基甲硅烷基锂物种已被证明是通过在三（N，N-四亚甲基）磷酰三胺（TPPA）作为活化剂的存在下用甲基锂处理六烷基二硅烷而容易地产生的，其可以被硼亲电试剂捕获以提供甲硅烷基硼酸酯，包括期待已久的Me 3Si-B（pin）。
Trialkylsilyllithium species have turned out to be facilely generated by treating hexaalkyldisilanes with methyllithium in the presence of tris(N,N-tetramethylene)phosphoric triamide (TPPA) as an activator, which can be trapped by boron electrophiles to afford silylboronic esters including long-awaited Me3Si–B(pin).