A SiPM-based isotropic-3D PET detector X'tal cube with a three-dimensional array of 1 mm3 crystals
A SiPM-based isotropic-3D PET detector X'tal cube with a three-dimensional array of 1 mm3 crystals
复制标题
DOI：
10.1088/0031-9155/56/21/003
复制
发表时间：
2011-11
影响因子：
3.5
通讯作者：
T. Yamaya;T. Mitsuhashi;Takahiro Matsumoto;N. Inadama;F. Nishikido;E. Yoshida;H. Murayama;H. Kawai;M. Suga;Mitsuo Watanabe
中科院分区：
文献类型：
--
作者：
T. Yamaya;T. Mitsuhashi;Takahiro Matsumoto;N. Inadama;F. Nishikido;E. Yoshida;H. Murayama;H. Kawai;M. Suga;Mitsuo Watanabe
我们正在开发一种新的，通用的各向同性三维PET探测器X 'tal立方体，在所有三维空间分辨率高。该探测器的研究挑战是通过用硅光电倍增管（SiPMs）覆盖分段晶体块的六个面来实现闪烁光子的有效探测。在本文中，我们开发了X 'tal立方体的第二个原型，用于概念验证。我们的目标是实现一个最终的探测器与1.0 mm 3立方晶体，在对比我们以前的发展使用3.0 mm 3立方晶体。晶体块由尺寸为0.993 × 0.993 × 0.993 mm 3的氧硅酸镥钆（LGSO）晶体的16 × 16 × 16阵列组成。将晶体光学粘合在一起，内部不插入任何反射器，并且将96个多像素光子计数器（MPPC，S10931- 50 P，即六个面，每个面具有4 × 4阵列的MPPC）光学耦合到晶体块的表面，每个光子计数器具有3.0 × 3.0 mm 2的敏感面积。几乎所有的4096个晶体都是通过Anger型计算识别的，这是由于在晶体块和光导之间插入了微调的反射片。为了提高边缘附近的晶体的识别性能，将形成0.5mm宽的带的反射片放置成覆盖从边缘开始的第二行的晶体的一半。由于闪烁光子的有效探测，在511 keV处获得了12.7%的能量分辨率，对于所有晶体段具有几乎均匀的光输出。
We are developing a novel, general purpose isotropic-3D PET detector X'tal cube which has high spatial resolution in all three dimensions. The research challenge for this detector is implementing effective detection of scintillation photons by covering six faces of a segmented crystal block with silicon photomultipliers (SiPMs). In this paper, we developed the second prototype of the X'tal cube for a proof-of-concept. We aimed at realizing an ultimate detector with 1.0 mm3 cubic crystals, in contrast to our previous development using 3.0 mm3 cubic crystals. The crystal block was composed of a 16 × 16 × 16 array of lutetium gadolinium oxyorthosilicate (LGSO) crystals 0.993 × 0.993 × 0.993 mm3 in size. The crystals were optically glued together without inserting any reflector inside and 96 multi-pixel photon counters (MPPCs, S10931-50P, i.e. six faces each with a 4 × 4 array of MPPCs), each having a sensitive area of 3.0 × 3.0 mm2, were optically coupled to the surfaces of the crystal block. Almost all 4096 crystals were identified through Anger-type calculation due to the finely adjusted reflector sheets inserted between the crystal block and light guides. The reflector sheets, which formed a belt of 0.5 mm width, were placed to cover half of the crystals of the second rows from the edges in order to improve identification performance of the crystals near the edges. Energy resolution of 12.7% was obtained at 511 keV with almost uniform light output for all crystal segments thanks to the effective detection of the scintillation photons.