Traditional Chinese medical therapy for erectile dysfunction.
Traditional Chinese medical therapy for erectile dysfunction.
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中医治疗勃起功能障碍
DOI：
10.21037/tau.2017.03.02
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发表时间：
2017-04
影响因子：
2
通讯作者：
Liu J
中科院分区：
文献类型：
--
作者：
Li H;Jiang H;Liu J
传统中医（TCM），包括针灸和中药，被用作增加勃起功能障碍（艾德）疗效的替代疗法。中医药治疗ED的疗效及机制已被大量研究所探讨，针灸治疗艾德的疗效目前仍存在争议。部分中药可能通过激活一氧化氮合酶（NOS）-环磷酸鸟苷（cGMP）通路、增加环磷酸腺苷（cAMP）表达、升高睾酮水平、降低细胞内Ca 2+浓度、下调转化生长因子β1（TGFβ1）/Smad 2信号通路或改善氧化应激等途径改善勃起功能。
Traditional Chinese medicine (TCM), including acupuncture and Chinese herbs, is used as an alternative therapy to increase the curative effect for erectile dysfunction (ED). A large number of studies have been conducted to investigate the effect and mechanism of TCM for treating ED. The therapeutic effect of acupuncture on ED is still controversial at present. However, some Chinese herbs exhibited satisfying outcomes and they might improve erectile function by activating nitric oxide synthase (NOS)-cyclic guanosine monophosphate (cGMP) pathway, increasing cyclic adenosine monophosphate (cAMP) expression, elevating testosterone level, reducing intracellular Ca2+ concentration, down-regulating transforming growth factor β1 (TGFβ1)/Smad2 signaling pathway, or ameliorating the oxidative stress.