Visual field loss in optic disc drusen patients correlates with central retinal artery blood velocity patterns
Visual field loss in optic disc drusen patients correlates with central retinal artery blood velocity patterns
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DOI：
10.1111/aos.12314
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发表时间：
2014-06-01
影响因子：
3.4
通讯作者：
Stalmans, Ingeborg
中科院分区：
文献类型：
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作者：
Pinto, Luis Abegao;Vandewalle, Evelien;Stalmans, Ingeborg
目的：（1）应用彩色多普勒超声对视盘玻璃疣（optic disc drusen，ODD）患者的球后循环进行研究;（2）探讨原发性开角型青光眼（primary open-angle glaucoma，POAG）患者球后血流动力学的差异。排除有眼外伤或眼部疾病（包括血管相关疾病）病史的受试者。Kruskal-Wallis和斯皮尔曼的相关性检验进行比较和探讨血流动力学参数和视野damage.ResultsSixty患者之间的相关性被包括在三组之间，平均分为。ODD患者视网膜中央动脉（CRA）收缩期和舒张期血流速度低于健康人，但与青光眼组无差异（p> 0.05）。
Purpose(1) To characterize the retrobulbar circulation in patients with optic disc drusen (ODD) using colour Doppler imaging; (2) to explore the differences in retrobulbar hemodynamics in patients with primary open-angle glaucoma (POAG).MethodsRetrospective analysis using three diagnostic groups: patients with ODD, age-matched healthy controls and age- and visual defect-matched patients with POAG. Subjects with history of ocular trauma or ocular diseases including vascular-related diseases were excluded. Kruskal-Wallis and Spearman's correlation tests were performed to compare and explore the correlations between the hemodynamic parameters and visual field damage.ResultsSixty patients were included and equally divided between the three groups. Patients with ODD had lower systolic and diastolic flow velocities in the central retinal artery (CRA) when compared to healthy individuals, but no difference was found with the glaucoma group (p