Healing of cavitary bone defects
Healing of cavitary bone defects
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DOI：
10.1007/s00590-011-0831-9
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发表时间：
2012-02
影响因子：
1.7
通讯作者：
T. Kučera;K. Urban;Stavroula Ragkou
中科院分区：
文献类型：
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作者：
T. Kučera;K. Urban;Stavroula Ragkou
背景：本文对良性肿瘤或肿瘤样病变引起的骨缺损的愈合进行了回顾性研究。我们评估了患者使用自体骨移植物或β-磷酸三钙（β-TCP）或两种成分混合物后的治疗结果。方法采用X线片测量缺损的初始体积、随访期的体积、充填材料的吸收和骨小梁的形成。通过统计分析，我们寻求依赖于骨愈合的初始体积的缺陷，骨的类型，患者的年龄，性别和weight-bearing.ResultsDuring 6年期间，从2003年至2009年，87例骨缺损（平均体积15 cm 3）。骨愈合的重要因素仍然是体积的缺陷，并在大缺陷的情况下，有一个有限的进展，小梁形成到中央part. ConclusionsAutobiles骨移植仍然是金标准，在骨缺损的愈合。β-TCP适用于自体植骨量不足或骨缺损达4 cm 3的病例，尤其是骨骺或干骺端。
BackgroundIt has been a retrospective review of healing of bone defects, due to benign tumours or tumour-like lesions. We evaluated the therapeutical outcome in patients after use of either autologous bone grafts, or β-tricalcium phosphate (β-TCP), or mixture of both components. We tried to find indications for β-TCP application.MethodsThe initial volume of defects, as well as, their volume in the follow-up period resorption of the filling materials and trabeculation of the defects were measured using radiographs. By means of statistical analysis, we sought a dependence of bone healing on the initial volume of the defect, type of bone involved, patient’s age, gender and weight-bearing.ResultsDuring the period of 6 years from 2003 to 2009, 87 patients with bone defects (average volume 15 cm3) were included. Significant factor for bone healing remains the volume of the defect, and in case of large defects, there was a restricted progress of trabeculation into the central part.ConclusionsAutologous bone grafts remain the gold standard in the healing of bone defects. β-TCP may be indicated in cases where there is insufficient amount of autologous bone grafts or in cases of bone defects up to 4 cm3particularly in epiphysis or metaphysis.