The Alopecia Areata Consensus of Experts (ACE) study part II: Results of an international expert opinion on diagnosis and laboratory evaluation for alopecia areata
The Alopecia Areata Consensus of Experts (ACE) study part II: Results of an international expert opinion on diagnosis and laboratory evaluation for alopecia areata
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DOI：
10.1016/j.jaad.2020.09.028
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发表时间：
2021-05-08
影响因子：
13.8
通讯作者：
Sinclair, Rodney D.
中科院分区：
文献类型：
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作者：
Meah, Nekma;Wall, Dmitri;Sinclair, Rodney D.
背景资料：我们以前报道了斑秃专家共识的研究，提出了一个国际专家意见的治疗结果为alopecia areata.Objective：报告结果的斑秃专家共识的国际专家意见的诊断和实验室评价为Alopecia areata.Methods：50头发专家从5大洲被邀请参加了3轮德尔菲过程。结果：在148个问题中，82个（55%）获得专家一致意见。第一轮148个问题中有10个达成了共识（7%）。第二轮在77个问题中的47个（61%）达成共识。最后的面对面会议在32个问题中的25个（78%）达成了共识。实验室评估的共识最大（14个问题中的12个[86%]），其次是斑秃的诊断（14个问题中的11个[79%]）。总体而言，发病机制取得了最少的类别共识（31 68个问题[46%]）。局限性：这项研究有低的代表性，从非洲，南美洲，和亚洲。结论：有专家共识方面的流行病学，发病机制，临床特征，诊断，实验室评估，和预后指标斑秃。这项研究还强调了未来的临床研究可以针对解决斑秃患者护理中未解决的假设的领域。
Background: We previously reported the Alopecia Areata Consensus of Experts study, which presented results of an international expert opinion on treatments for alopecia areata.Objective: To report the results of the Alopecia Areata Consensus of Experts international expert opinion on diagnosis and laboratory evaluation for alopecia areata.Methods: Fifty hair experts from 5 continents were invited to participate in a 3-round Delphi process. Consensus threshold was set at greater than or equal to 66%.Results: Of 148 questions, expert consensus was achieved in 82 (55%). Round 1 consensus was achieved in 10 of 148 questions (7%). Round 2 achieved consensus in 47 of 77 questions (61%). The final face-to-face achieved consensus in 25 of 32 questions (78%). Consensus was greatest for laboratory evaluation (12 of 14 questions [86%]), followed by diagnosis (11 of 14 questions [79%]) of alopecia areata. Overall, etiopathogenesis achieved the least category consensus (31 of 68 questions [46%]).Limitations: The study had low representation from Africa, South America, and Asia.Conclusion: There is expert consensus on aspects of epidemiology, etiopathogenesis, clinical features, diagnosis, laboratory evaluation, and prognostic indicators of alopecia areata. The study also highlights areas where future clinical research could be directed to address unresolved hypotheses in alopecia areata patient care.