Microscopic examination of bronchial epithelium in children.
Microscopic examination of bronchial epithelium in children.
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儿童支气管上皮的显微镜检查。
DOI：
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发表时间：
1960
期刊：
影响因子：
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通讯作者：
L. Garfinkel
中科院分区：
文献类型：
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作者：
O. Auerbach;A. Stout;E. Hammond;L. Garfinkel
在一项对大量成年人(包括吸烟者和不吸烟者以及患有和不患有肺癌的受试者)的扩展研究中，作者确信，吸烟者表现出必须被认为是癌前病变的支气管粘膜变化，这种变化的数量取决于香烟消耗量的增加。成年非吸烟者可能会表现出极少量的癌前病变。研究一组不吸烟的受试者似乎很重要，这些受试者的气管、支气管树受到吸入污染物的刺激程度最低。因此，选择了35名15岁以下的儿童，并对他们的气管和支气管树进行了研究。这些儿童死于各种原因，有或没有肺炎和支气管溃疡。特别感兴趣的是了解是否可以识别任何癌前病变，以及肺炎和支气管溃疡对支气管粘膜的影响。
In an extended study of a large number of adults, including smokers and nonsmokers and subjects with and without lung cancer, the writers have been convinced that persons who are cigarette smokers show changes in the bronchial mucosa which must be considered precancerous and which increase in amount depending upon an increase in the wnsumption of cigarettes. Adult nonsmokers may show a minimal amount of such precancerous changes. It seemed important to study a group of subjects who were nonsmokers and whose tracheobronchial trees had been subjected to a minimal amount of irritation from inhaled contaminants. Accordingly, a group of 35 children less than fifteen years of age were selected, and their tracheobronchial trees were studied. These children had died from various causes with and without pneumonia and bronchial ulceration. It was of special interest to learn whether or not any precancerous changes could be recognized and what had been the effects of pneumonia and bronchial ulceration on the bronchial mucosa.