Isolated office hypertension:: are there any markers of future blood pressure status?
Isolated office hypertension:: are there any markers of future blood pressure status?
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DOI：
10.1097/00126097-200010000-00001
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发表时间：
2000-10-01
影响因子：
1.3
通讯作者：
Libretti, A
中科院分区：
文献类型：
--
作者：
Colombo, F;Catarame, S;Libretti, A
背景：将动态血压监测引入临床实践，定义了一种称为“孤立性办公室高血压”的临床状况。目的：研究单纯办公室高血压患者的长期收缩压和舒张压变化，并确定是否存在能够识别哪些患者将发展为持续性高血压的标志物。随机诊室收缩压或/和舒张压超过140/90 mmHg，平均日间动态血压为130/84 mmHg或更低。在招募时，每位患者都进行了“基线检查”，包括体格评估，24小时动态血压监测，在24 h动态监测结束时进行心算测试。结果在最终研究的173例患者中，102例（58.9%）发生持续性高血压，动态收缩压和舒张压均升高。在基线检查时，将患者分为两组。A组包括第一小时平均动态收缩压和舒张压130/84 mmHg或teas的患者; B组包括第一小时平均动态收缩压和舒张压大于130/84 mmHg的患者。在心算测试中，收缩压和心率值仅在B组患者中显著增加。102例患者谁成为高血压的随访检查时，84（82%）属于组B。结论这些数据表明，孤立的办公室高血压可能确实是一个过渡状态的发展为持续性高血压。此外，第一个小时内的平均动态血压值可以被认为是发生持续性高血压风险较高的标志。血压监测5：249-254（C）2000 Lippincott威廉姆斯&威尔金斯。
Background The introduction of ambulatory blood pressure monitoring into clinical practice has defined a clinical condition called 'isolated office hypertension'.Objective The aim of this study was to evaluate the long-term systolic and diastolic blood pressure changes in patients with isolated office hypertension and to identify the presence of markers capable of identifying which patients will develop sustained hypertension.Methods All the 407 patients enrolled had a random office systolic or/and diastolic blood pressure of over 140/90 mmHg and a mean daytime ambulatory blood pressure of 130/84 mmHg or less. At enrolment, each patient underwent a 'baseline examination' made up of a physical evaluation, a 24 h ambulatory blood pressure monitoring, and a mental arithmetic test performed at the end of the 24 h ambulatory monitoring.Results Of the 173 patients finally studied, 102 (58.9%) developed sustained hypertension with an increase in both ambulatory systolic and diastolic blood pressure. At the time of the baseline examination, the patients were divided into two groups. Group A included patients with mean ambulatory systolic and diastolic blood pressures in the first hour of 130/84 mmHg or teas; group B included patients with mean ambulatory systolic and diastolic pressures in the first hour of greater than 130/84 mmHg. During the mental arithmetic test, the systolic and heart rate values increased significantly only in group B patients. Of the 102 patients who had become hypertensive by the time of the follow-up examination, 84 (82%) belonged to group B.Conclusion These data suggest that isolated office hypertension may indeed be a transitional state towards the development of sustained hypertension. Moreover, the mean ambulatory blood pressure value during the first hour can be considered to be a marker of a higher risk of developing sustained hypertension. Blood Press Monit 5:249-254 (C) 2000 Lippincott Williams & Wilkins.