Divergence of RNA editing among Arabidopsis species.
Divergence of RNA editing among Arabidopsis species.
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DOI：
10.1016/j.plantsci.2018.12.009
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发表时间：
2019-03
期刊：
影响因子：
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通讯作者：
A. Kawabe;Hazuka Y. Furihata;Yudai Tsujino;Takahiro Kawanabe;Sota Fujii;Takanori Yoshida
中科院分区：
文献类型：
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作者：
A. Kawabe;Hazuka Y. Furihata;Yudai Tsujino;Takahiro Kawanabe;Sota Fujii;Takanori Yoshida
RNA 编辑通过将植物细胞器基因组中的 C 核苷酸替换为 U 来改变 RNA 序列。有时，远缘物种的 RNA 编辑状态有所不同。 RNA 编辑状态的保守和变化模式使得评估影响 RNA 编辑功能方面的进化机制成为可能。在这项研究中，分析了拟南芥物种叶绿体基因组中 RNA 编辑的差异，以确定 RNA 编辑中的 9 次丢失和 1 次增加。 A 中的所有更改。拟南芥谱系是由叶绿体基因组序列的变化引起的，而 A. lyrata/hallerilineage 可能是由于核编辑因子的独特变化所致。 A 中 RNA 编辑缺失一次。 lyratawas 是由 PPR 基因 OTP80 缺陷引起的。 RNA编辑的变化大约每两百万年发生一次，并且在功能重要的位点没有观察到。这些结果强调了 RNA 编辑状态的保守性，表明 RNA 编辑在进化过程中的重要性。
RNA editing altered the RNA sequence by replacing the C nucleotide to U in the organellar genomes of plants. RNA editing status sometimes differed among distant species. The pattern of conservation and variation of RNA editing status made it possible to evaluate evolutionary mechanisms impacting functional aspects of RNA editing. In this study, divergence of RNA editing in the chloroplast genome amongArabidopsisspecies was analyzed to determine 9 losses and 1 gain in RNA editing. All changes inA. thalianalineage resulted from changes to the chloroplast genome sequence, whereas changes in theA. lyrata/hallerilineage were possibly due to exclusive changes in the nuclear editing factors. One loss of RNA editing inA. lyratawas caused by a deficiency in the PPR geneOTP80. The changes in RNA editing occurred approximately every two million years and were not observed at functionally important sites. These results highlight the conserved nature of RNA editing status suggesting the importance of RNA editing during evolution.