EFFECT OF URINARY EXTRACTS FROM SALT-LOADED MAN ON URINARY SODIUM EXCRETION BY RAT
EFFECT OF URINARY EXTRACTS FROM SALT-LOADED MAN ON URINARY SODIUM EXCRETION BY RAT
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DOI：
10.1038/ki.1972.62
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发表时间：
1972-01-01
影响因子：
19.6
通讯作者：
DEWARDEN.HE
中科院分区：
文献类型：
--
作者：
BROWN, PR;KOUTSAIMANIS, KG;DEWARDEN.HE
盐负荷人尿提取物对大鼠尿钠排泄的影响。将从低和高氯化钠摄入量的受试者制备的尿提取物注射到清醒的水负荷大鼠中。当盐耗尽时，从受试者中获得的尿提取物不会引起尿钠排泄或尿流量的显著增加。从受试者中获得的尿提取物在盐负荷时引起尿钠排泄和尿流量的显着增加。可以得出结论，来自受试者的尿液当盐负载时含有利钠物质。
Effect of urinary extracts from salt loaded man on urinary sodium excretion of the rat. Urinary extracts prepared from subjects on low and high intakes of sodium chloride were injected into conscious water-loaded rats. Urinary extracts obtained from the subjects when salt-depleted did not cause a significant rise in urinary sodium excretion or urine flow. Urinary extracts obtained from the subjects when salt-loaded caused a significant rise in urinary sodium excretion and urine flow. It is concluded that the urine from the subjects when salt-loaded contains a natriuretic substance.