Amphotericin B 2-morpholinoethylamide diaspartate, a new water soluble derivative of the antibiotic. Synthesis and biological properties.

Amphotericin B 2-morpholinoethylamide diaspartate, a new water soluble derivative of the antibiotic. Synthesis and biological properties.
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两性霉素 B 2-吗啉乙酰胺二天冬氨酸盐,一种新型水溶性抗生素衍生物。

DOI:
10.7164/antibiotics.43.680
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发表时间:
1990
期刊:
The Journal of antibiotics
影响因子:
--
通讯作者:
L. Micossi
L. Micossi
中科院分区:
--
文献类型:
--
作者:
Andrzej Czerwinski;T. Zieniawa;Edward Borowski;L. Micossi

文献摘要

被引文献

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本文报道了一种新的水溶性抗生素衍生物--二磺酸吗啉乙酰胺的合成方法,并给出了体外生物学数据。
The synthesis of amphotericin B 2-morpholinoethylamide diaspartate, a new water soluble antibiotic derivative with improved selective toxicity is described and in vitro biological data are presented.