Delineation of organs at risk involved in swallowing for radiotherapy treatment planning

Delineation of organs at risk involved in swallowing for radiotherapy treatment planning
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DOI:
10.1016/j.radonc.2011.05.015
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发表时间:
2011-12-01
影响因子:
5.7
通讯作者:
Bijl, Hendrik P.
Bijl, Hendrik P.
中科院分区:
医学1区
文献类型:
--
作者:
Christianen, Miranda E. M. C.;Langendijk, Johannes A.;Bijl, Hendrik P.

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背景和目的:放射治疗是头颈癌常用的一种治疗方法,可单用或联合化疗。为了充分报道、比较和解释放射治疗的后遗症,重要的是要根据明确和统一的指南来描述危险器官(OAR)。材料与方法:通过对人体头颈部的解剖学分析和文献复习,由专家小组描述了基于CT的最相关SWOARs的勾画指南。结果和结论:本文描述了潜在的SWOARs的机构勾画指南,并附有基于CT的插图,提供了所描绘的结构及其对应的解剖边界的实例。这篇论文对于确保对未来关于这些SWOAR中的剂量分布与治疗后吞咽功能障碍的不同方面之间的关系的报告的充分解释至关重要。(C)2011爱思唯尔爱尔兰有限公司。保留所有权利。放射治疗与肿瘤学101(2011)394-402
Background and purpose: Radiotherapy, alone or combined with chemotherapy, is a treatment modality used frequently in head and neck cancer. In order to report, compare and interpret the sequelae of radiation treatment adequately, it is important to delineate organs at risk (OARs) according to well-defined and uniform guidelines. The aim of this paper was to present our institutional Computed Tomography (CT)-based delineation guidelines for organs in the head and neck at risk for radiation-induced swallowing dysfunction (SWOARs).Material and methods: After analyses of the human anatomy of the head and neck area and literature review, CT-based guidelines for delineation of the most relevant SWOARs were described by a panel of experts.Results and conclusions: This paper described institutional guidelines for the delineation of potential SWOARs, accompanied by CT-based illustrations presenting examples of the delineated structures and their corresponding anatomic borders. This paper is essential to ensure adequate interpretation of future reports on the relationship between dose distribution in these SWOARs and different aspects of post-treatment swallowing dysfunction. (C) 2011 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 101 (2011) 394-402