An Investigation of Homes with High Concentrations of PCDDs, PCDFs, and/or Dioxin-Like PCBs in House Dust
An Investigation of Homes with High Concentrations of PCDDs, PCDFs, and/or Dioxin-Like PCBs in House Dust
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DOI：
10.1080/15459620802694975
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发表时间：
2009-01-01
影响因子：
2
通讯作者：
Towey, Tim
中科院分区：
文献类型：
--
作者：
Franzblau, Alfred;Zwica, Lynn;Towey, Tim
作为密歇根大学二恶英暴露研究的一部分，在密歇根州五个县的选定地区，采用基于人口的抽样设计，对来自764户家庭的房屋灰尘中的29种多氯二苯并对二恶英、多氯二苯并呋喃和二恶英样多氯联苯的同系物进行了测量，这些同系物具有世界卫生组织共识的毒性当量因子。20个家庭的房屋灰尘总毒性当量高于平均值2.5个标准差（即，定义为离群值）。这项后续调查描述了离群值的房屋灰尘测量和相应的土壤测量，并探讨了这些毒素在房屋灰尘的可能来源。室内灰尘异常值中的同系物分布各不相同，并且占主导地位（即，总毒性当量的50%）由多氯二苯并对二恶英（n = 9）、多氯二苯并呋喃（n = 1）或二恶英类多氯联苯（n = 9）产生。仅在三个案例中确定了可能的室内灰尘污染源。在两个案例中，灰尘污染似乎与住宅附近的污染土壤有关;在一个案例中，污染与住宅内的污染源（地毯垫）有关。在大多数情况下，无法确定室内灰尘污染的来源，但似乎可能与室内未定性的来源有关。[可提供本条的补充材料。请访问出版商的《职业和环境卫生杂志》在线版，获取以下免费补充资源：一份PDF文件，其中包含基线和灰尘异常值访谈问题的摘要，以及包含各种室内灰尘和土壤样本中多氯联苯、多氯二苯并对二恶英和多氯二苯并呋喃浓度的表格。
As part of the University of Michigan Dioxin Exposure Study, the 29 congeners of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls that have World Health Organization consensus toxic equivalency factors were measured in house dust from 764 homes using a population-based sampling design over selected regions in five Michigan counties. Twenty homes had a total toxic equivalency in house dust that was more than 2.5 standard deviations above the mean (i.e., defined to be outliers). This follow-up investigation describes the outlier house dust measurements and corresponding soil measurements and explores possible sources of these toxins in house dust. The congener distributions in the house dust outliers varied and were dominated (i.e., 50% of the total toxic equivalency) by either polychlorinated dibenzo-p-dioxins (n = 9), polychlorinated dibenzofurans (n = 1), or dioxin-like polychlorinated biphenyls (n = 9). Likely sources of contamination of house dust were identified in only three cases. In two cases, dust contamination appeared to be related to contaminated soil adjacent to the home; in one case, contamination was related to a source within the home (a carpet pad). In most cases, the source(s) of contamination of house dust could not be identified but appeared likely to be related to uncharacterized sources within the homes. [Supplementary materials are available for this article. Go to the publisher's online edition of the Journal of Occupational and Environmental Hygiene for the following free supplemental resource: a PDF file containing a summary of baseline and dust outlier interview questions and tables containing PCB, PCDD, and PCDF concentrations in various samples of house dust and soil.].