Intraindividual stability of hair cortisol concentrations
Intraindividual stability of hair cortisol concentrations
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DOI：
10.1016/j.psyneuen.2011.08.007
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发表时间：
2012-05-01
影响因子：
3.7
通讯作者：
Kirschbaum, Clemens
中科院分区：
文献类型：
--
作者：
Stalder, Tobias;Steudte, Susann;Kirschbaum, Clemens
对人类头发中皮质醇的分析为回顾性评估长期累积皮质醇分泌提供了一种有前途的方法。使用该方法的隐含假设是，在没有重大生活变化的情况下，头发皮质醇浓度显示出高水平的个体内稳定性，即单根头发皮质醇评估表现出相当大的性状特异性，并且仅在较小程度上受到状态依赖性因素的影响。在这里，我们提供了两项独立研究的数据，这些研究检查了头发皮质醇水平的个体稳定性模式。在研究 I 中，45 名参与者在相隔一年的两个采样点接受了检查。在研究 II 中，64 人提供了三个采样点的数据，采样点每隔两个月进行一次。在这两项研究中，在每个时间点都对头发进行了采样，并评估了相关的心理社会和头发相关变量。两项研究的结果一致显示，重复的头发皮质醇测量具有很强的重测关联性（“r”在 0.68 到 0.79 之间，“p”
The analysis of cortisol in human hair constitutes a promising method for the retrospective assessment of cumulative cortisol secretion over extended periods of time. An implicit assumption underlying the use of this method is that in the absence of major life changes hair cortisol concentrations show a high level of intraindividual stability, i.e. single hair cortisol assessments exhibit considerable trait-specificity and are only to a smaller extent influenced by state-dependent factors. Here, we present data from two independent studies examining patterns of intraindividual stability in hair cortisol levels. In study I, 45 participants were examined at two sampling points carried out one year apart from each other. In study II, 64 individuals provided data at three sampling points which occurred at two-month intervals. In both studies, at each time point hair was sampled and relevant psychosocial and hair-related variables were assessed. Results of both studies consistently revealed strong test-retest associations for repeated hair cortisol measurements ('r's between 0.68 and 0.79, 'p's