Mosquitocidal bacterial toxins: Diversity, mode of action and resistance phenomena
Mosquitocidal bacterial toxins: Diversity, mode of action and resistance phenomena
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DOI：
10.1590/s0074-02762000000700034
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发表时间：
2000-01-01
影响因子：
2.8
通讯作者：
Nielsen-LeRoux, C
中科院分区：
文献类型：
--
作者：
Charles, JF;Nielsen-LeRoux, C
对双翅目幼虫（蚊子和黑蝇）有活性的细菌包括多种苏云金芽孢杆菌和B。球形芽孢杆菌菌株，以及侧孢短芽孢杆菌和双酶梭菌的分离物。所有显示不同的光谱和活动水平与毒素的性质，主要是在孢子形成过程中产生的。本文介绍了主要灭蚊毒素的结构和作用方式，ir？这与它们在蚊子和/或黑蝇幼虫控制中的潜在用途有关。对已对B具有高度抗性的蚊子的实验室和现场群体进行调查。SphaericusBin毒素已经表明涉及几种抗性机制，一些影响毒素/受体结合步骤，其他未知。
Bacteria active against dipteran larvae (mosquitoes and black flies) include a wide variety of Bacillus thuringiensis and B. sphaericus strains, as well as isolates of Brevibacillus laterosporus and Clostridium bifermentans. All display different spectra and levels of activity correlated with the nature of the toxins, mainly produced during the sporulation process. This paper describes the structure and mode of action of the main mosquitocidal toxins, ir? relationship with their potential use in mosquito and/or black fly larvae control. investigations with laboratory and field colonies of mosquitoes that have become highly resistant to the B. sphaericus Bin toxin have shown that several mechanisms of resistance are involved, some affecting the toxin/receptor binding step, others unknown.