Rapid three-dimensional segmentation of the carotid bifurcation from serial MR images
Rapid three-dimensional segmentation of the carotid bifurcation from serial MR images
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DOI：
10.1115/1.429646
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发表时间：
2000-02-01
影响因子：
1.7
通讯作者：
Steinman, DA
中科院分区：
文献类型：
--
作者：
Ladak, HM;Milner, JS;Steinman, DA
目前计算血流动力学的趋势是采用来自离体或体内成像的真实模型。此类研究通常会产生一系列图像，首先必须从中单独提取管腔边界（即二维分割），然后依次重建以产生三维管腔表面几何形状。在本文中，我们提出了一种快速的三维分割技术，结合了这两个步骤，基于膨胀的虚拟气球的想法。本文将该三维技术应用于正常志愿者颈动脉分岔血流的有限元网格划分和CFD建模。用三维技术生成的网格计算的墙体剪应力图与用网格生成的结构计算的结果吻合得很好。除了将提取管腔表面所需的时间从几小时减少到几分钟之外，我们的方法易于学习和使用，并且需要最少的用户干预，这可能会增加血液动力学和血管疾病定量和纵向研究的准确性和精密度。[s0148 - 0731(00) 00201 - 6]。
The current trend in computational hemodynamics is to employ realistic models derived from ex vivo or in vivo imaging. Such studies typically produce a series of images from which the lumen boundaries must first be individually extracted (i.e., two-dimensional segmentation), and then serially reconstructed to produce the three-dimensional lumen surface geometry. In this paper, we present a rapid three-dimensional segmentation technique that combines these two steps, based on the idea of an expanding virtual balloon. This three-dimensional technique is demonstrated in application to finite element meshing and CFD modeling of flow in the carotid bifurcation of a normal volunteer imaged with black blood MRI. Wall shear stress patterns computed using a mesh generated with the three-dimensional technique agree well with those computed using a mesh generated construction. In addition to reducing the time required to extract the lumen surface from hours to minutes, our approach is easy to learn and use and requires minimal user intervention, which can potentially increase the accuracy and precision of quantitative and longitudinal studies of hemodynamics and vascular disease. [S0148-0731(00)00201-6].