Selective Recognition of d-Aldohexoses in Water by Boronic Acid-Functionalized, Molecularly Imprinted Cross-Linked Micelles.
Selective Recognition of d-Aldohexoses in Water by Boronic Acid-Functionalized, Molecularly Imprinted Cross-Linked Micelles.
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DOI：
10.1021/jacs.6b04613
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发表时间：
2016-08-10
影响因子：
15
通讯作者：
Zhao Y
中科院分区：
文献类型：
--
作者：
Awino JK;Gunasekara RW;Zhao Y
使用碳水化合物的 4-乙烯基苯基硼酸酯衍生物在交联胶束内进行分子印迹，提供了对碳水化合物模板具有选择性的水溶性纳米颗粒受体。如果糖的 C2 或 C4 处发生一次羟基倒置，或者如果发生两次或更多次倒置，则这些受体可以实现 d-己醛糖的完全分化。由于疏水相互作用增加，具有疏水性聚糖的糖苷表现出更强的结合。
Molecular imprinting within cross-linked micelles using 4-vinylphenylboronate derivatives of carbohydrates provided water-soluble nanoparticle receptors selective for the carbohydrate templates. Complete differentiation of d-aldohexoses could be achieved by these receptors if a single inversion of hydroxyl occurred at C2 or C4 of the sugar or if two or more inversions took place. Glycosides with a hydrophobic aglycan displayed stronger binding due to increased hydrophobic interactions.