Tricuspid Regurgitation in Hypoplastic Left Heart Syndrome Mechanistic Insights From 3-Dimensional Echocardiography and Relationship With Outcomes
Tricuspid Regurgitation in Hypoplastic Left Heart Syndrome Mechanistic Insights From 3-Dimensional Echocardiography and Relationship With Outcomes
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DOI：
10.1161/circimaging.113.001161
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发表时间：
2014-09-01
影响因子：
7.5
通讯作者：
Khoo, Nee Scze
中科院分区：
文献类型：
--
作者：
Kutty, Shelby;Colen, Timothy;Khoo, Nee Scze
Background-Our purpose was to test the following hypotheses: (1) patients with hypoplastic left heart syndrome who develop significant tricuspid regurgitation (TR) or require tricuspid valve (TV) surgery in the medium term have detectable TV abnormalities by 3-dimensional echocardiography (3DE) prestage 1 palliation and (2) TR is associated with reduced survival and increased TV intervention.Methods and Results-Infants were prospectively studied with 3DE and 2DE prestage 1 and followed up for the end points of TR, TV surgery, transplantation, or death. From prestage 1 3DE, spatial coordinates of TV annulus and leaflets were extracted; annulus size, leaflet area, prolapse volume, tethering volume, bending angle, and papillary muscle angle were measured. TR was assessed prestage 1 and at latest follow-up. Of 70 patients, 62 (88.6%) had mild or less TR and 8 (11.4%) had moderate or greater TR prestage 1. Prestage 1 tethering volume correlated to leaflet area (r=0.736; P
