Frequency-dependent activation of glucose utilization in the superior cervical ganglion by electrical stimulation of cervical sympathetic trunk.
Frequency-dependent activation of glucose utilization in the superior cervical ganglion by electrical stimulation of cervical sympathetic trunk.
复制标题
通过电刺激颈交感干，频率依赖性地激活颈上神经节中的葡萄糖利用。
DOI：
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发表时间：
1983
影响因子：
11.1
通讯作者：
L. Sokoloff
中科院分区：
文献类型：
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作者：
P. Yarowsky;M. Kadekaro;L. Sokoloff
电刺激横断的颈交感神经干的远端残端产生葡萄糖利用的频率依赖性激活，通过脱氧[14 C]葡萄糖方法测量，在麻醉大鼠的上级颈神经节。频率依赖性福尔斯落在0-15 Hz之间;在20 Hz时，葡萄糖利用的激活不大于15 Hz时。切断颈交感神经干的上级颈神经节的传入神经阻滞不会降低麻醉大鼠神经节中葡萄糖的利用率。这些结果表明，在神经支配的神经结构的能量代谢率，至少在部分，调节的电输入的脉冲频率的结构，这种调节可能是一个重要组成部分的代谢活动的耦合机制的功能活动的神经系统。
Electrical stimulation of the distal stump of the transected cervical sympathetic trunk produces a frequency-dependent activation of glucose utilization, measured by the deoxy[14C]glucose method, in the superior cervical ganglion of the urethane-anesthetized rat. The frequency dependence falls between 0-15 Hz; at 20 Hz the activation of glucose utilization is no greater than at 15 Hz. Deafferentation of the superior cervical ganglion is transection of the cervical sympathetic trunk does not diminish the rate of glucose utilization in the ganglion in the urethane-anesthetized rat. These results indicate that the rate of energy metabolism in an innervated neural structure is, at least in part, regulated by the impulse frequency of the electrical input to the structure, and this regulation may be an essential component of the mechanism of the coupling of metabolic activity to functional activity in the nervous system.