Reliability and sensitivity of the self-report of physician-diagnosed gout in the campaign against cancer and heart disease and the atherosclerosis risk in the community cohorts.
Reliability and sensitivity of the self-report of physician-diagnosed gout in the campaign against cancer and heart disease and the atherosclerosis risk in the community cohorts.
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DOI：
10.3899/jrheum.100418
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发表时间：
2011-01
期刊：
影响因子：
--
通讯作者：
Gelber AC
中科院分区：
文献类型：
--
作者：
McAdams MA;Maynard JW;Baer AN;Köttgen A;Clipp S;Coresh J;Gelber AC
在流行病学研究中，痛风通常由自我报告来定义。然而，自我报告痛风的有效性是不确定的。我们评估了癌症和心脏病运动（CLUE II）和社区动脉粥样硬化风险（ARIC）队列中医生诊断痛风自我报告的可靠性和敏感性。CLUE II队列包括12,912名在2000年、2003年或2007年问卷中自我报告痛风状况的个体。我们使用Cohen 's κ统计来计算可靠性，即在多于1份问卷中报告痛风的参与者的百分比。ARIC队列包括11,506名在访问4时自我报告痛风状态的个体。我们将医院对痛风的出院诊断或痛风特异性药物的使用作为计算自我报告的、医生诊断的痛风敏感性的标准。在2000年自我报告医生诊断痛风并随后回答2003年问卷的437名CLUE II参与者中，75%在2003年报告痛风（κ = 0.73）。在2000年报告痛风的271名参与者中，73%在2007年的随访问卷中再次报告痛风（κ = 0.63）。在ARIC中，196名参与者在第4次访问之前符合痛风的定义，并在第4次访问时自我报告他们的痛风状态。医生诊断的痛风自我报告的敏感性为84%。准确性在性别和种族亚组之间相似，但在高尿酸血症和教育阶层之间存在差异。这两个基于人群的美国队列表明，医生诊断痛风的自我报告具有良好的可靠性和敏感性。因此，自我报告的医生诊断痛风是适当的流行病学研究。
Gout is often defined by self-report in epidemiologic studies. Yet the validity of self-reported gout is uncertain. We evaluated the reliability and sensitivity of the self-report of physician-diagnosed gout in the Campaign Against Cancer and Heart Disease (CLUE II) and the Atherosclerosis Risk in the Community (ARIC) cohorts. The CLUE II cohort comprises 12,912 individuals who self-reported gout status on either the 2000, 2003, or 2007 questionnaires. We calculated reliability as the percentage of participants reporting having gout on more than 1 questionnaire using Cohen’s κ statistic. The ARIC cohort comprises 11,506 individuals who self-reported gout status at visit 4. We considered a hospital discharge diagnosis of gout or use of a gout-specific medication as the standard against which to calculate the sensitivity of self-reported, physician-diagnosed gout. Of the 437 CLUE II participants who self-reported physician-diagnosed gout in 2000, and subsequently answered the 2003 questionnaire, 75% reported gout in 2003 (κ = 0.73). Of the 271 participants who reported gout in 2000, 73% again reported gout at the 2007 followup questionnaire (κ = 0.63). In ARIC, 196 participants met the definition for gout prior to visit 4 and self-reported their gout status at visit 4. The sensitivity of a self-report of physician-diagnosed gout was 84%. Accuracy was similar across sex and race subgroups, but differed across hyperuricemia and education strata. These 2 population-based US cohorts suggest that self-report of physician-diagnosed gout has good reliability and sensitivity. Thus, self-report of a physician diagnosis of gout is appropriate for epidemiologic studies.
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影响因子：
--
作者：
Lawrence, Reva C.;Felson, David T.;Wolfe, Frederick
通讯作者：
Wolfe, Frederick
影响因子：
--
作者：
Gelber, AC;Klag, MJ;Hochberg, MC
通讯作者：
Hochberg, MC
影响因子：
27.4
作者：
Picavet, HSJ;Hazes, JMW
通讯作者：
Hazes, JMW
DOI：
10.1002/art.22474
发表时间：
2007-02-15
期刊：
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
影响因子：
--
作者：
Harrold, Leslie R.;Saag, Kenneth G.;Platt, Richard
通讯作者：
Platt, Richard
影响因子：
7.2
作者：
Gurwitz, JH;Kalish, SC;Avorn, J
通讯作者：
Avorn, J