Immune Thrombocytopenia.
Immune Thrombocytopenia.
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DOI：
10.1056/nejmc1913324
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发表时间：
2020-03
期刊：
影响因子：
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通讯作者：
N. Cooper;W. Ghanima
中科院分区：
文献类型：
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作者：
N. Cooper;W. Ghanima
Affected individuals can develop red or purple spots on the skin caused by bleeding just under the skin's surface. Small spots of bleeding under the skin are called purpura and larger spots are called ecchymoses. People with immune thrombocytopenia can have significant bleeding episodes, such as nose bleeds (epistaxis) or bleeding in the moist lining (mucosae) of the mouth. In severe cases, individuals may have gastrointestinal bleeding or blood in the urine or stool, or heavy and prolonged menstrual bleeding (menorrhagia). In very rare instances, bleeding inside the skull (intracranial hemorrhage) can occur, which can be life-threatening. A greater reduction in platelet numbers is often associated with more frequent bleeding episodes and an increased risk of severe bleeding.
