The Danish National Patient Registry: a review of content, data quality, and research potential.
The Danish National Patient Registry: a review of content, data quality, and research potential.
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DOI：
10.2147/clep.s91125
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发表时间：
2015
影响因子：
3.9
通讯作者：
Sørensen HT
中科院分区：
文献类型：
--
作者：
Schmidt M;Schmidt SA;Sandegaard JL;Ehrenstein V;Pedersen L;Sørensen HT
丹麦国家患者登记处(DNPR)是世界上最古老的全国性医院登记处之一，被广泛用于研究。许多研究已经验证了用于识别DNPR中的健康事件的算法，但这些报告是零散的，并且不存在概述。回顾DNPR的内容、数据质量和研究潜力。我们考察了DNPR的背景、历史、目标、内容和分类系统。我们搜索了PubMed和《丹麦医学杂志》，创建了验证研究的参考书目。我们还纳入了检索到的论文中引用的研究或我们事先知道的研究。回顾了与DNPR数据相关的方法学考虑。1977-2012年，DNPR登记了8,085,603人，其中住院患者7,268,857人，门诊5,953,405人，急诊科联系人5,097,300人。DNPR提供全国范围内详细的行政和临床数据的纵向登记。它记录了自1977年以来从丹麦非精神病院出院的所有患者的信息，以及自1995年以来精神科住院患者、急诊科和门诊专科诊所接触者的信息。对于每个患者接触者，根据国际疾病分类记录一次初级诊断和可选的二次诊断。DNPR为识别疾病、检查、某些医院内医疗治疗和外科手术提供了数据来源。可以研究住院率和治疗率的长期时间趋势。疾病和治疗的阳性预测值差异很大(<；15%-100%)。DNPR数据可以在患者层面与来自其他丹麦行政登记、临床登记、随机对照试验、人口调查和流行病学现场研究的数据联系起来，使研究人员能够重建整个人口的个人生活和健康轨迹。DNPR是流行病学研究的宝贵工具。然而，在解释研究结果时，它的优点和局限性都必须被考虑，并且其临床数据的持续验证是至关重要的。
The Danish National Patient Registry (DNPR) is one of the world’s oldest nationwide hospital registries and is used extensively for research. Many studies have validated algorithms for identifying health events in the DNPR, but the reports are fragmented and no overview exists. To review the content, data quality, and research potential of the DNPR. We examined the setting, history, aims, content, and classification systems of the DNPR. We searched PubMed and the Danish Medical Journal to create a bibliography of validation studies. We included also studies that were referenced in retrieved papers or known to us beforehand. Methodological considerations related to DNPR data were reviewed. During 1977–2012, the DNPR registered 8,085,603 persons, accounting for 7,268,857 inpatient, 5,953,405 outpatient, and 5,097,300 emergency department contacts. The DNPR provides nationwide longitudinal registration of detailed administrative and clinical data. It has recorded information on all patients discharged from Danish nonpsychiatric hospitals since 1977 and on psychiatric inpatients and emergency department and outpatient specialty clinic contacts since 1995. For each patient contact, one primary and optional secondary diagnoses are recorded according to the International Classification of Diseases. The DNPR provides a data source to identify diseases, examinations, certain in-hospital medical treatments, and surgical procedures. Long-term temporal trends in hospitalization and treatment rates can be studied. The positive predictive values of diseases and treatments vary widely (<15%–100%). The DNPR data are linkable at the patient level with data from other Danish administrative registries, clinical registries, randomized controlled trials, population surveys, and epidemiologic field studies – enabling researchers to reconstruct individual life and health trajectories for an entire population. The DNPR is a valuable tool for epidemiological research. However, both its strengths and limitations must be considered when interpreting research results, and continuous validation of its clinical data is essential.