A Review of Global Epidemiology and Response to Meningococcal Disease Outbreaks among Men Who Have Sex with Men, 2001-2018
A Review of Global Epidemiology and Response to Meningococcal Disease Outbreaks among Men Who Have Sex with Men, 2001-2018
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DOI：
10.1007/s40471-018-0170-z
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发表时间：
2018-12-01
影响因子：
3.3
通讯作者：
Mbaeyi, Sarah A.
中科院分区：
文献类型：
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作者：
Oliver, Sara E.;Mbaeyi, Sarah A.
综述目的与其他男性相比，与男性发生性关系的男性（MSM）先前已被证明患脑膜炎球菌病的风险增加。我们总结了全球流行病学和公共卫生应对的MSM人群脑膜炎球菌病爆发。最近的调查结果至少有10个血清群C脑膜炎球菌病爆发的MSM自2001年以来已报告。由于无法确定病例之间的流行病学联系，对男男性行为者疫情的调查和应对往往受到阻碍，在许多疫情中，建议接种疫苗的目标人群随着时间的推移而扩大。在一些疫情期间，使用了独特的沟通方法，包括使用应用程序和社交媒体，以确定密切接触者并传达健康信息。虽然在美国，感染HIV的MSM患散发性脑膜炎球菌病的风险更高，但其他因素也可能导致MSM中的暴发。由于脑膜炎奈瑟氏菌尿道炎的增加，最近在美国男子的报告，虽然其在MSM.SummaryMeningococcal疾病之间的传播的作用仍然不清楚。HIV感染的作用和N.目前正在调查脑膜炎的传播情况，以便进一步了解脑膜炎球菌病和在这一人群中爆发的情况。在MSM人群中爆发脑膜炎球菌病期间，疫苗接种仍然是主要的预防和控制策略。
Purpose of ReviewMen who have sex with men (MSM) have been previously shown to be at increased risk for meningococcal disease compared to other men. We summarized the global epidemiology and public health response to meningococcal disease outbreaks among MSM.Recent FindingsAt least ten outbreaks of serogroup C meningococcal disease among MSM have been reported since 2001. Investigation of and response to outbreaks among MSM have often been hampered by an inability to identify epidemiologic links among cases, and the target population recommended for vaccination has been expanded over time in many outbreaks. Unique communication methods, including the use of apps and social media, have been used during some outbreaks to identify close contacts and to communicate health messages. Although HIV-infected MSM have a higher risk of sporadic meningococcal disease in the USA, other factors are likely contributing to outbreaks among MSM. An increase in urethritis due to Neisseria meningitidis has recently been reported in US men, though its role in meningococcal disease transmission among MSM remains unclear.SummaryMeningococcal disease outbreaks among MSM raise questions regarding possible unique risk factors in this population. The role of HIV infection and mode of N. meningitidis transmission are being investigated to provide further insights into meningococcal disease and outbreaks in this population. Vaccination remains the primary prevention and control strategy during meningococcal disease outbreaks among MSM.