Antiretroviral drug resistance and routine therapy, Cameroon

Antiretroviral drug resistance and routine therapy, Cameroon
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DOI:
10.3201/eid1206.050860
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发表时间:
2006-06-01
影响因子:
11.8
通讯作者:
Delaporte, E
Delaporte, E
中科院分区:
医学2区
文献类型:
--
作者:
Laurent, C;Kouanfack, C;Delaporte, E

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在喀麦隆一家艾滋病毒/艾滋病门诊常规接受高效抗逆转录病毒治疗的128名患者中,16.4%的患者在中位数10个月后出现抗药性。其中,12.5%对核苷逆转录酶抑制剂(NRTI)耐药,10.2%对非NRTI耐药,2.3%对蛋白水解酶抑制剂耐药。
Among 128 patients routinely receiving highly active antiretroviral therapy in an HIV/AIDS outpatient clinic in Cameroon, 16.4% had drug resistance after a median of 10 months. Of these, 12.5% had resistance to nucleoside reverse transcriptase inhibitors (NRTIs), 10.2% to non-NRTIs, and 2.3% to protease inhibitors.