BIOSYNTHESIS OF THE ANTIBIOTIC ACTINORHODIN - ANALYSIS OF BLOCKED MUTANTS OF STREPTOMYCES-COELICOLOR
BIOSYNTHESIS OF THE ANTIBIOTIC ACTINORHODIN - ANALYSIS OF BLOCKED MUTANTS OF STREPTOMYCES-COELICOLOR
复制标题
DOI：
10.7164/antibiotics.40.340
复制
发表时间：
1987-03-01
影响因子：
3.3
通讯作者：
FLOSS, HG
中科院分区：
文献类型：
--
作者：
COLE, SP;RUDD, BAM;FLOSS, HG
从天蓝色链霉菌（Streptomycescoelicolor）的两种Ⅴ类act突变体中分离出放线菌紫素的两种单体前体，并测定了它们的结构。一种是已知的抗生素卡拉芬净（2），另一种是新化合物（6）。讨论了它们与放线菌紫素生物合成的关系。
From two types of class V act mutants of Streptomyces coelicolor two monomeric precursors of actinorhodin have been isolated and their structures determined. One is the known antibiotic kalafungin (2) and the other a new compound (6). Their relationship to actinorhodin biosynthesis is discussed.