N‐ACETYL‐l‐ASPARTIC ACID CONTENT OF HUMAN NEURAL TUMOURS AND BOVINE PERIPHERAL NERVOUS TISSUES
N‐ACETYL‐l‐ASPARTIC ACID CONTENT OF HUMAN NEURAL TUMOURS AND BOVINE PERIPHERAL NERVOUS TISSUES
复制标题
人神经肿瘤和牛周围神经组织的 N-乙酰基-L-天冬氨酸含量
作者：
J. Nadler;J. Cooper
摘要-摘要-利用人类神经系统肿瘤研究N-乙酰-L-天冬氨酸（NAA）的细胞分布。星形胶质细胞肿瘤中约含0.144 μmol/g。少突胶质细胞瘤和髓母细胞瘤含有更多的量。然而，NAA的水平在所有研究的胶质瘤低于正常人的白色物质。脑膜瘤和听神经鞘瘤中未检测到NAA。如果这些结果可以作为正常组织的代表，它们意味着NAA的主要神经元定位。
Abstract— Abstract‐Tumors of the human nervous system were utilized to investigate the cellular distribution of N‐acetyl‐L‐aspartic acid (NAA). Astroglial tumours contained about 0.144 μmol/g. Oligodendrogliomas and medulloblastomas contained somewhat larger amounts. However, the level of NAA in all gliomas studied was less than that of normal human white matter. NAA was undetectable in meningiomas and acoustic neurinomas. If these results may be taken as representative of normal tissue, they imply a predominantly neuronal localization for NAA.