Quantitative analysis of miroestrol and kwakhurin for standardisation of Thai miracle herb "Kwao Keur' (Pueraria mirifica) and establishment of simple isolation procedure for highly estrogenic miroestrol and deoxymiroestrol

Quantitative analysis of miroestrol and kwakhurin for standardisation of Thai miracle herb "Kwao Keur' (Pueraria mirifica) and establishment of simple isolation procedure for highly estrogenic miroestrol and deoxymiroestrol
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DOI:
10.1080/14786419.2012.695370
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发表时间:
2013-03-01
影响因子:
2.2
通讯作者:
Chansakaow, Sunee
Chansakaow, Sunee
中科院分区:
化学3区
文献类型:
--
作者:
Shimokawa, Satoko;Kumamoto, Takuya;Chansakaow, Sunee

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使用独立的溶剂系统建立了通过 HPLC 对 miroestrol (1) 和 kwakhurin (3) 进行定量分析的方法,从而实现了市售泰国神奇草药 Kwao Keur' 的标准化,该药草已通过野葛根 (Pueraria mirifica) 进行鉴定。还提出了从野葛根中分离出高雌激素性的微雌醇 (1) 和脱氧微雌醇 (2) 的简单方法。
Quantitative analysis of miroestrol (1) and kwakhurin (3) by HPLC, leading to standardisation of commercially available Thai miracle herb Kwao Keur' which has been identified with Pueraria mirifica, was established using independent solvent systems. The simple isolation procedure of highly estrogenic miroestrol (1) and deoxymiroestrol (2) from P. mirifica was also proposed.