Derivation of chondrocyte and osteoblast reporter mouse embryonic stem cell lines.
Derivation of chondrocyte and osteoblast reporter mouse embryonic stem cell lines.
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DOI：
10.1002/dvg.22849
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发表时间：
2015-03
期刊：
影响因子：
1.5
通讯作者：
Maye, Peter
中科院分区：
文献类型：
--
作者：
Fu, Yu;Maye, Peter
With the establishment of methods that provide evidence for the generation of chondrocyte and osteoblast cell types from ESCs, there is a need for reagents that will enable their further characterization. Here we report on the derivation of chondrocyte and osteoblast reporter ESCs from previously generated and characterized transgenic mouse lines, Collagen type 2 alpha 1(Col2a1)-ECFP, Bone Sialoprotein (BSP)-Topaz, and BSP-Topaz/Dentin Matrix Protein 1 (DMP1)-Cherry dual reporter mice. Col2a1-ECFP is highly expressed in chondrocytes, while BSP-Topaz and DMP1-Cherry are highly expressed in osteoblasts and osteocytes, respectively. These new skeletal reporter mouse ESC lines will serve as valuable reagents to investigate the functionality of ESC derived chondrocyte and osteoblast cell types.
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影响因子：
1.5
作者：
Strecker, Sara;Fu, Yu;Liu, Yaling;Maye, Peter
通讯作者：
Maye, Peter
影响因子：
3.9
作者：
Wray, Jason;Kalkan, Tuzer;Smith, Austin G.
通讯作者：
Smith, Austin G.
影响因子：
64.5
作者：
Silva J;Nichols J;Theunissen TW;Guo G;van Oosten AL;Barrandon O;Wray J;Yamanaka S;Chambers I;Smith A
通讯作者：
Smith A
影响因子：
64.8
作者：
Ying, Qi-Long;Wray, Jason;Smith, Austin
通讯作者：
Smith, Austin
影响因子：
4.6
作者：
Zhao, Jiangang;Li, Songhui;Nakayama, Naoki
通讯作者：
Nakayama, Naoki