Proteinase inhibitors of bovine nasal cartilage.
Proteinase inhibitors of bovine nasal cartilage.
复制标题
牛鼻软骨的蛋白酶抑制剂。
作者：
P. Roughley;G. Murphy;A. Barrett
牛鼻软骨提取液与1 M-胍氯化物分级超滤。低分子量物质的凝胶色谱分离出三种不同的级分，其对（a）胶原酶（22000摩尔重量）具有抑制活性，(b)巯基蛋白酶组织蛋白酶B和木瓜蛋白酶（13000摩尔重量），和（c）胰蛋白酶和其它丝氨酸蛋白酶（7000摩尔重量）。
Extracts from bovine nasal cartilage with 1 M-guanidinium chloride were fractionated by ultrafiltration. Gel chromatography of the low-molecular-weight material resolved three distinct fractions with inhibitory activity against (a) collagenases (22000 mol.wt.), (b) thiol proteinases cathepsin B and papain (13000 mol.wt.), and (c) trypsin and other serine proteinases (7000 mol.wt.).