A foodborne outbreak of sapovirus linked to catered box lunches in Japan
A foodborne outbreak of sapovirus linked to catered box lunches in Japan
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DOI：
10.1007/s00705-012-1394-8
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发表时间：
2012-10-01
影响因子：
2.7
通讯作者：
Minagawa, Hiroko
中科院分区：
文献类型：
--
作者：
Kobayashi, Shinichi;Fujiwara, Noriko;Minagawa, Hiroko
SAV是世界范围内急性病毒性胃肠炎的常见病因，近年来SAV的暴发变得更加频繁。2010年1月，日本爱知县、岐阜县和三叠县爆发了由萨弗病毒引起的急性胃肠炎。这种疾病与吃了一家餐饮公司准备的盒饭有很大关系。总体而言，3827人中有655人(17.1%)出现胃肠道症状。在9名生病的人中有7人检测到SAV，在餐饮公司52名食品加工人员中有7人检测到SAV，但所有检测样本的诺沃克病毒和肠道致病菌均为阴性。RT-PCR产物的序列分析表明，来自患病人群和食品从业人员的SAV毒株的核苷酸序列是相同的。对检测到的SAV毒株进行基因分型，确定为SAV基因I2。这是日本最大规模的食源性萨普病毒暴发。
Sapovirus (SaV) is a common cause of acute viral gastroenteritis worldwide, and SaV outbreaks have become more frequent in recent years. In January 2010, an outbreak of acute gastroenteritis due to SaV occurred in Aichi, Gifu and Mie Prefectures, Japan. The illness was strongly associated with eating a delivered box lunch prepared by one catering company. In total, 655 (17.1 %) of 3827 individuals developed gastroenteritic symptoms. SaV was detected in seven of the nine people who became ill and in seven of the 52 food handlers at the catering company, but all the tested samples were negative for norovirus and enteropathogenic bacteria. Sequence analysis of RT-PCR products indicated that the nucleotide sequences of SaV strains from the people who became ill and the food handlers were identical. The detected SaV strains were genogrouped as SaV genotype I.2. This was the largest foodborne outbreak of sapovirus in Japan.