Corticospinal excitability during painful self-stimulation in humans: a transcranial magnetic stimulation study
Corticospinal excitability during painful self-stimulation in humans: a transcranial magnetic stimulation study
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DOI：
10.1016/j.neulet.2003.12.016
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发表时间：
2004-05-06
影响因子：
2.5
通讯作者：
Porro, CA
中科院分区：
文献类型：
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作者：
Fadiga, L;Craighero, L;Porro, CA
我们研究了健康志愿者在主动（自我刺激）或被动（外部诱导）对锋利或钝的指尖施加持续的有害和无害的机械刺激时，其手指头的皮质脊髓活动模式的变化。结果表明，为了将手指按在有害刺激上，并产生与按在无害刺激上相同的力，运动皮层在运动单元的招募方面采用了一种特殊的策略。这反映在皮质脊髓兴奋性的增加（通过对侧初级运动皮层经颅磁刺激引起的运动电位显示）和激动剂肌肉的肌电图活动。可能与运动单元同步增加有关。2004爱思唯尔爱尔兰有限公司版权所有。
We investigated changes in the corticospinal pattern of activity in health), volunteers during sustained noxious and non-noxious mechanical stimulation of the first hand digit, resulting from active (self-stimulation) or passive (exterrially-induced) pressing against a sharp or blunted tip. The results indicate that, in order to press a finger onto a noxious stimulus with the same force generated to press onto a non-noxious one, the motor cortex adopts a peculiar strategy in terms of recruitment of motor units. This is reflected by an increase of corticospinal excitability (as revealed by motor potentials evoked by transcranial magnetic stimulation of the contralateral primary motor cortex) and EMG activity of agonist muscles. possibly related to an increase of motor unit synchronization. (C) 2004 Elsevier Ireland Ltd. All rights reserved.