Changes in the provision of post-exposure prophylaxis for HIV after sexual exposure following introduction of guidelines and publicity campaigns
Changes in the provision of post-exposure prophylaxis for HIV after sexual exposure following introduction of guidelines and publicity campaigns
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DOI：
10.1258/ijsa.2007.007216
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发表时间：
2008-04-01
影响因子：
1.4
通讯作者：
Benn, P.
中科院分区：
文献类型：
--
作者：
Roedling, S.;Reeves, I.;Benn, P.
2004年7月，英国性健康和艾滋病毒协会（BASHH）出版了性接触后接触后预防指南（PEPSE），特伦斯·希金斯信托基金会（THT）发起了一项在男男性行为者（MSM）中促进接触后预防的运动。我们评估了随后PEPSE出席率的变化。从临床数据库中确定2004年要求PEPSE的个体。比较运动前后的临床资料、暴露特征及随访情况。有197/216 (91%)PEP出勤的数据。性暴露后要求进行PEP的比例在活动后显著增加。大多数开始PEPSE的人是男同性恋者，男同性恋者的比例从运动前的36/46（78%）显著增加到运动后的76/80（95%）。大多数处方都是在高危人群中开的，而且是在指南范围内开的。启动时间和完井率不变。在THT运动和BASHH指南的引入之后，获得PEPSE的机会增加了。需要促进尽早启动PEPSE并改进完成情况和后续工作。
In July 2004, British Association of Sexual Health and HIV (BASHH) published guidelines for post-exposure prophylaxis following sexual exposure (PEPSE) and the Terence Higgins Trust (THT) launched a campaign promoting PEPSE among men who have sex with men (MSM). We evaluated subsequent changes in PEPSE attendances. Individuals requesting PEPSE in 2004 were identified from clinic databases. Comparisons of clinical data, exposure characteristics and follow-up were made pre and post campaign. Data were available for 197/216 (91%) PEP attendances. The proportion requesting PEP following sexual exposure increased significantly following the campaign. The majority commencing PEPSE were MSM, with the proportion of MSM increasing significantly from 36/46 (78%) pre to 76/80 (95%) following the campaign. Most prescriptions were in high-risk groups and within guidelines. Times to initiation and completion rates were unchanged. Access to PEPSE following the THT campaign and introduction of BASHH guidelines increased. Promotion of earlier initiation of PEPSE and improvement of completion and follow-up is required.