SURFACE INACTIVATION OF BACTERIAL VIRUSES AND OF PROTEINS
SURFACE INACTIVATION OF BACTERIAL VIRUSES AND OF PROTEINS
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DOI：
10.1085/jgp.31.5.417
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发表时间：
1948-01-01
影响因子：
3.8
通讯作者：
ADAMS, MH
中科院分区：
文献类型：
--
作者：
ADAMS, MH
对大肠杆菌有活性的T组的7种细菌病毒在气-液界面处迅速灭活。这种失活的动力学，无论是通过在空气中摇动还是通过用N2鼓泡引起的，都是一级反应。这种失活可以通过加入足够的蛋白质来防止，以使气-液界面保持在相对于蛋白质的饱和条件下。本文指出并讨论了通过振荡使病毒失活与蛋白质表面变性之间的相似性。
The 7 bacterial viruses of the T group active against Escherichia coli are rapidly inactivated at gas-liquid interfaces. The kinetics of this inactivation, whether brought about by shaking in air, or by bubbling with N2, are those of a 1st order reaction. This inactivation may be prevented by addition of enough protein to maintain the gas-liquid interface in a saturated condition with respect to protein. The analogy between this inactivation of viruses by shaking, and the surface denatura-tion of proteins is pointed out and discussed.