Bioelectrical impedance for detecting upper limb lymphedema in nonlaboratory settings.
Bioelectrical impedance for detecting upper limb lymphedema in nonlaboratory settings.
复制标题
DOI：
10.1089/lrb.2008.1003
复制
发表时间：
2009
影响因子：
1.4
通讯作者：
Kidd N
中科院分区：
文献类型：
--
作者：
Ridner SH;Dietrich MS;Deng J;Bonner CM;Kidd N
单频生物电阻抗已被用于临床和研究环境，以测量细胞外液在手臂。它的易用性和低风险的用户错误表明，这种测量方法可能具有优势，用于非实验室（基于社区）的环境相比，其他测量方法。本研究的目的是评估在非实验室环境中使用单频生物电阻抗检测上肢水肿的可行性。使用标准化的协议，阻抗比健康正常女性，乳腺癌幸存者与水肿，乳腺癌幸存者没有水肿进行了比较，在一个直立的位置坐在有利于使用实验室以外的设置（社区为基础的环境）。健康正常对照组和无淋巴水肿的乳腺癌幸存者组的比率非常相似，置信区间几乎完全重叠。然而，这些值与水肿存活组的评估值有显著差异（p < 0.001）。这些研究结果表明，单频生物电阻抗测定的阻抗比可以作为在非实验室设置时，使用标准化的协议，水肿的标志物。
Single-frequency bioelectrical impedance has been used in clinical and research settings to measure extracellular fluid in arms. Its ease of use and low risk of user error suggests this measurement method may have advantages for use in nonlaboratory (community-based) environments when compared to other measurement methods. The purpose of this study was to evaluate the feasibility of using single-frequency bioelectrical impedance to detect upper limb lymphedema in nonlaboratory settings. Using a standardized protocol, impedance ratios among healthy normal women, breast cancer survivors with lymphedema, and breast cancer survivors without lymphedema were compared with participants seated in an upright position conducive for use outside laboratory settings (community-based environments). Ratios of healthy normal controls and breast cancer survivor groups without lymphedema were very similar, with almost complete overlap in confidence intervals. However, those values were markedly different from the values assessed in the survivor group with lymphedema (p < 0.001). These findings suggest impedance ratios determined by single-frequency bioelectrical impedance can be used as markers for lymphedema in nonlaboratory settings when a standardized protocol is used.