From perception to behavior: The neural circuits underlying prey hunting in larval zebrafish.

From perception to behavior: The neural circuits underlying prey hunting in larval zebrafish.
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DOI:
10.3389/fncir.2023.1087993
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发表时间:
2023
影响因子:
3.5
通讯作者:
--
中科院分区:
医学3区
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神经系统的一个关键挑战是从环境中提取相关信息并做出适当的行为反应。斑马鱼幼体为研究这些感知过程和感觉运动转换提供了令人兴奋的机会。捕猎是斑马鱼的一种本能行为,需要大脑提取并组合不同属性的感觉输入并形成适当的运动输出。由于斑马鱼幼虫大脑尺寸小且透明,因此可以对全脑活动进行光学记录,以揭示猎物狩猎和捕获所涉及的神经机制。在这篇综述中,我们讨论了幼虫斑马鱼大脑如何处理视觉信息来识别和定位猎物、控制响应猎物的运动命令生成的神经回路、如何通过内部状态和经验调节狩猎行为,以及该领域的一些突出问题。
A key challenge for neural systems is to extract relevant information from the environment and make appropriate behavioral responses. The larval zebrafish offers an exciting opportunity for studying these sensing processes and sensory-motor transformations. Prey hunting is an instinctual behavior of zebrafish that requires the brain to extract and combine different attributes of the sensory input and form appropriate motor outputs. Due to its small size and transparency the larval zebrafish brain allows optical recording of whole-brain activity to reveal the neural mechanisms involved in prey hunting and capture. In this review we discuss how the larval zebrafish brain processes visual information to identify and locate prey, the neural circuits governing the generation of motor commands in response to prey, how hunting behavior can be modulated by internal states and experience, and some outstanding questions for the field.
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