[Clinical study of preoperative radiotherapy of bladder cancer].
[Clinical study of preoperative radiotherapy of bladder cancer].
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膀胱癌术前放疗的临床研究[J].
DOI：
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发表时间：
1990
期刊：
影响因子：
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通讯作者：
M. Hamami
中科院分区：
文献类型：
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作者：
H. Shimada;K. Imanaka;T. Hashimura;S. Hirota;K. Yonezawa;T. Soezima;K. Izumiyama;M. Kono;K. Goji;M. Hamami
自1982年5月至1987年11月，对33例膀胱癌患者行术前放疗(20Gy5Fr)加全膀胱切除术。总的3年生存率为70%。T1和T2的3年生存率为100%，而T3和T4的3年生存率分别为55%和0%。33例术前TUR-BT确认术前T期23例。23例患者中有7例(30%)被认为是分期下降。TCI 0例(0%)，T1 2例(67%)，T2 3例(50%)，T3 2例(18%)，T4 0例(0%)。这种术前放疗方案被认为对T1和T2膀胱癌是有利的，但对T3和T4肿瘤是不合适的。因此，认为对T3、T4膀胱癌进行大剂量放疗和术后化疗是必要的。
From May 1982 to Nov. 1987, 33 patients with bladder carcinoma were treated with preoperative radiotherapy (20 Gy/5fr) and total cystectomy. The over all 3-year survival rate was 70%. For T1 and T2, 3-year survival rate was 100%, but only 55% and 0% for T3 and T4 respectively. In 23 out of 33 patients, preoperative T-stage was confirmed by TUR-BT. Down-Staging was recognized in 7 out of 23 patients (30%). They were 0 out of 1 patients for Tcis (0%), 2 of 3 for T1 (67%), 3 of 6 for T2 (50%), 2 of 11 for T3 (18%) and 0 of 2 for T4 (0%). This protocol of preoperative radiotherapy is thought to be favorable for T1 and T2 bladder carcinoma, but inadequate for T3 and T4 tumors. Consequently, it is considered that higher dose radiotherapy and postoperative chemotherapy are necessary for T3 and T4 bladder carcinoma.