Near misses of ACR/EULAR criteria for remission: effects of patient global assessment in Boolean and index-based definitions
Near misses of ACR/EULAR criteria for remission: effects of patient global assessment in Boolean and index-based definitions
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DOI：
10.1136/annrheumdis-2012-201519
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发表时间：
2012-10-01
影响因子：
27.4
通讯作者：
Aletaha, Daniel
中科院分区：
文献类型：
--
作者：
Studenic, Paul;Smolen, Josef S.;Aletaha, Daniel
背景 美国风湿病学会/欧洲抗风湿联盟最近发布了类风湿性关节炎 (RA) 的缓解标准。 目的 量化仅满足四个布尔标准中的三个的患者比例以及患者总体评估 (PGA) 在缓解情况下的相关性。 方法 从观察性前瞻性 RA 数据库中，确定仅满足四个布尔标准中的三个的患者的首次就诊。对逻辑回归和描述性分析进行处理，还通过基于指数（简化疾病活动指数 (SDAI)）的定义来定义缓解，并将结果与评估者总体评估 (EGA) 进行比较。结果 52% 的患者至少接受过一次就诊，仅满足三个标准（未满足的为：PGA 61%；关节肿胀 20%；关节压痛 13%；C 反应蛋白 7%）。 67% 不符合 PGA 标准的患者进行了 EGA
Background The American College of Rheumatology/European League Against Rheumatism remission criteria for rheumatoid arthritis (RA) have been published recently.Objective To quantify the proportions of patients fulfilling only three of the four Boolean criteria and the relevance of patient global assessment (PGA) in context of remission.Methods From an observational prospective RA database the first visit of patients, fulfilling just three of the four Boolean criteria was identified. Logistic regression and descriptive analyses were processed, also defining remission by index-based (Simplified Disease Activity Index (SDAI)) definition and comparing outcomes with the evaluator global assessment (EGA).Results 52% had at least one visit, fulfilling just three criteria (not fulfilled were: PGA 61%; swollen joints 20%; tender joints 13%; C-reactive-protein 7%). 67% of patients not fulfilling the PGA criterion had an EGA