Alcohol and cardiovascular disease.
Alcohol and cardiovascular disease.
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DOI：
10.1007/s11883-000-0054-8
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发表时间：
2000-11-01
影响因子：
5.8
通讯作者：
Rimm, E
中科院分区：
文献类型：
--
作者：
Rimm, E
适量饮酒可降低健康男性和女性患冠心病的风险。新的证据表明，70 多项流行病学研究中描述的这种关联是因果关系，部分可以通过酒精对血脂和凝血因子的有益作用来解释。最近，在成人糖尿病患者和既往患有心血管疾病的个体中，也有报道称酒精与心血管疾病之间呈负相关。尽管越来越多的证据强烈支持大多数人群适度饮酒对心血管有益，但对戒酒者开始每日饮酒的临床建议尚未得到文献证实，必须谨慎对待并根据个人情况给予。
Alcohol in moderation is associated with lower risk of coronary heart disease in healthy men and women. New evidence suggests that this association, described in over 70 epidemiologic studies, is causal and can be explained, in part, by alcohol's beneficial effects on serum lipids and clotting factors. Recently, the inverse association between alcohol and cardiovascular disease also has been reported in populations with adult-onset diabetes and among individuals with previous cardiovascular disease. Although mounting evidence strongly supports the cardiovascular benefits of moderate alcohol consumption in most populations, clinical advice to abstainers to initiate daily alcohol consumption has not yet been substantiated in the literature and must be taken with caution and given on an individual basis.