Microstructure and biocompatibility of porous-Ta/Ti-6Al-4 V component produced by laser powder bed fusion for orthopedic implants
Microstructure and biocompatibility of porous-Ta/Ti-6Al-4 V component produced by laser powder bed fusion for orthopedic implants
复制标题
DOI：
10.1016/j.matchar.2021.111554
复制
发表时间：
2021-10-30
影响因子：
4.7
通讯作者：
Zhou, Kechao
中科院分区：
文献类型：
--
作者：
Zhang, Taomei;Chen, Chao;Zhou, Kechao
钽因其优异的耐腐蚀性和生物相容性，作为一种优秀的骨科植入材料而受到越来越多的关注。然而，钽的高熔点和强氧亲和力使其制备难度和成本增加。此外，高昂的原材料成本也限制了钽的广泛应用。为了突破这些限制，通过激光粉末床熔融技术在ti - 6al - 4v基上成功制备了不同孔径的多孔钽涂层，构建了具有优异生物活性和骨整合能力的整体多孔ta / ti - 6al - 4v组件。钽与Ti-6Al-4V之间形成了较强的冶金结合，结合强度达460 MPa以上。多孔钽涂层被设计成具有强对称性的类金刚石结构。钽涂层的孔隙率为70%，孔径为447 ~ 865 μ m，其变形特征与天然松质骨极为相似。多孔Ta涂层的平均抗压屈服强度在5.8 ~ 24之间。2 MPa。多孔Ta涂层的平均压缩弹性模量（0.6 ~ 1.5 GPa）接近松质骨。耐腐蚀试验证明，经ta涂层的ti - 6al - 4v合金在模拟体液中具有优异的化学稳定性。体外实验表明，小鼠颅骨成骨前细胞在多孔钛涂层上具有良好的粘附和生长性能。因此，初步确定激光粉末床熔融定制的多孔ta / ti - 6al - 4v组件可以作为骨科植入的候选材料。
Tantalum is attracting more attention as an outstanding orthopedic implant material due to its excellent corrosion resistance and biocompatibility. However, the high melting point and strong oxygen affinity of tantalum make its preparation more difficult and costly. In addition, the high cost of raw materials also limits the wider application of tantalum. To break these limitations, porous tantalum coatings with different pore sizes were successfully prepared on Ti-6Al-4 V base by Laser Powder Bed Fusion, constructing an integral porous-Ta/ Ti-6Al-4 V component with excellent bioactivity and osteointegration capacity. A strong metallurgical bonding was formed between tantalum and Ti-6Al-4V, and the bonding strength is more than 460 MPa. The porous tantalum coating is designed as diamond-like structure with strong symmetry. The porosity of tantalum coatings is 70%, and the pore size ranges from 447 to 865 mu m. Its deformation characteristics are extremely similar to those of natural cancellous bone. The average compressive yield strength of the porous Ta coatings ranges from 5.8 to 24. 2 MPa. And the average compressive elastic modulus of porous Ta coatings (0.6-1.5 GPa) was close to that of cancellous bone. Corrosion resistance tests proved that the Ta-coated Ti-6Al-4 V alloy had an excellent chemical stability in simulated body fluid. In vitro tests showed that Mouse calvarial preosteoblasts presented a good adhesion and growth behavior on porous Ta coatings. Therefore, it is preliminarily determined that the customized porous-Ta/Ti-6Al-4 V component by Laser powder bed fusion can be a candidate material for orthopedic implantation.