Feasibility and preliminary efficacy of tantalum components in the management of acetabular reconstruction following periacetabular oncologic resection in primary malignancies.
Feasibility and preliminary efficacy of tantalum components in the management of acetabular reconstruction following periacetabular oncologic resection in primary malignancies.
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DOI：
10.1186/s40001-022-00777-x
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发表时间：
2022-08-17
影响因子：
4.2
通讯作者：
Sun, Wei
中科院分区：
文献类型：
--
作者：
Zan, Pengfei;Ma, Xiaojun;Wang, Hongsheng;Cai, Zhengdong;Shen, Jiakang;Sun, Wei
关键词：
本研究的目的是探讨钽组件在髋臼周围肿瘤切除术后髋臼缺损重建中的可行性和初步疗效。我们前瞻性地收集了2018年1月至2018年12月连续15例髋臼周围肿瘤切除术后应用钽组件进行髋臼重建的病例。该队列包括8名男性和7名女性患者，平均年龄47.6岁（33 - 67岁）。病理类型：软骨肉瘤（n = 9）、恶性骨巨细胞瘤（n = 3）、骨肉瘤（n = 3）。详细记录临床结果、功能和影像学结果以供分析。患者均接受有计划的肿瘤切除和钽组件重建，无人员伤亡；平均随访39.7个月（35 ~ 45个月）。平均手术时间4.0 h (3.0 ~ 6.0 h)，平均出血量1260 ml （800 ~ 2200 ml）。功能结局采用MSTS-93量表评定，平均评分为21.8分（12.0 ~ 26.0分），其中优3例，良11例，一般1例。术后1年随访Harris髋关节评分平均为79.1分（46.0 ~ 92.0分）。术后并发症3例（3/15,20.0%）：2例髋关节脱位在全麻下行闭合复位，髋关节外展支具固定6周；1例浅表感染，接受清创，伤口愈合延迟。肿瘤预后：1例随访8个月复发，行半盆腔截肢；另一例骨肉瘤复发伴肺转移并接受进一步化疗。随访期间未发生假体松动、移位或骨折。初步结果表明，在髋臼周围肿瘤切除术后髋臼重建中使用钽组件可合理改善假体的功能结局和早期稳定性。多孔钽组件有利于骨长入，这是一种潜在的替代现有的各种重建技术，以获得更好的功能结果。
The aim of the study was to investigate the feasibility and preliminary efficacy of tantalum components utility in the reconstruction of acetabular defects following periacetabular oncologic resection of primary malignancies. We prospectively collected a consecutive of 15 cases that were treated with tantalum components for acetabular reconstruction after periacetabular oncologic resection from January 2018 to December 2018. The cohort included 8 male and 7 female patients, with a mean age of 47.6 years (range, 33 to 67 years). Pathology types: chondrosarcoma (n = 9), malignant bone giant cell tumor (n = 3) and osteosarcoma (n = 3). Clinical outcomes, functional and radiographic results were recorded in detail for analysis. Patients received planned oncologic resection and tantalum components reconstruction without casualty; they were followed up with a mean of 39.7 months (35–45 months). The mean operation time was 4.0 h (3.0–6.0 h), and the mean blood loss was 1260 ml (800–2200 ml). Functional outcomes were assessed by MSTS-93 scale, with an average of 21.8 (12.0–26.0 scores), among which 3 cases were excellent, 11 were good and 1 was fair. The mean Harris Hip Score was 79.1scores (46.0–92.0 scores) at 1-year follow-up postoperatively. 3(3/15, 20.0%) cases experienced postoperative complications: 2 cases with hip dislocation received closed reduction under general anesthesia and were fixed with hip joint abduction braces for 6 weeks; one case had a superficial infection and received debridement with a delayed wound healing. Oncologic prognosis: one case relapsed at 8-month follow-up and received hemi-pelvic amputation; and another osteosarcoma patient experienced relapse with pulmonary metastasis and received further chemotherapy. No prosthetic loosening, displacement or fracture occurred during the follow-up period. Preliminary results suggested that the use of tantalum components in the management of acetabular reconstruction following periacetabular oncologic resection provided reasonable improvement on functional outcomes and early stability of the prostheses. Porous tantalum components are conducive to bony ingrowth, which is a potential alternative to various existing reconstruction techniques to achieve better functional outcomes.
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影响因子：
4.2
作者：
Bus MP;Szafranski A;Sellevold S;Goryn T;Jutte PC;Bramer JA;Fiocco M;Streitbürger A;Kotrych D;van de Sande MA;Dijkstra PD
通讯作者：
Dijkstra PD
自体股骨头植骨手术切除重建技术治疗原发性盆腔恶性肿瘤引起的部分髋臼缺损
影响因子：
3.8
作者：
Sun, Wei;Zan, Pengfei;Cai, Zhengdong
通讯作者：
Cai, Zhengdong
影响因子：
1.1
作者：
Angelini, Andrea;Calabro, Teresa;Ruggieri, Pietro
通讯作者：
Ruggieri, Pietro
影响因子：
4.2
作者：
Jansen, J. A.;van de Sande, M. A. J.;Dijkstra, P. D. S.
通讯作者：
Dijkstra, P. D. S.
盆腔恶性肿瘤切除后使用计算机辅助定制假体进行半骨盆重建的临床效果
影响因子：
3.5
作者：
Sun, Wei;Li, Jian;Cai, Zhengdong
通讯作者：
Cai, Zhengdong