The size of the myofibers in mature grafts of the mouse extensor digitorum longus muscle.

The size of the myofibers in mature grafts of the mouse extensor digitorum longus muscle.
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小鼠趾长伸肌成熟移植物中肌纤维的大小。

DOI:
10.1002/mus.880070307
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发表时间:
1984
期刊:
影响因子:
3.4
通讯作者:
Ontell,M
Ontell,M
中科院分区:
医学3区
文献类型:
--
作者:
Thomas,D;Klueber,K;Bourke,D;Ontell,M

文献摘要

相似文献

将稳定原位移植的小鼠趾长伸肌 (EDL) 的组织化学特征和移植物中的纤维类型直径分布与对照肌肉进行比较。基于肌原纤维 ATP 酶反应的组织化学纤维分型表明,移植物总纤维群中 1 型纤维占 < 1%,2a 型纤维占 30%,2b 型纤维占 69%。在 56 日龄和 156 日龄小鼠的对照肌肉中,1 型纤维占正常肌肉纤维总数的 <1%,2a 型纤维占 36%,2b 型纤维占 63%。稳定移植物中的再生肌纤维未能达到正常的纤维直径。 2b 型纤维比 2a 型纤维表现出更大的生长抑制作用。
The histochemical profile of stabilized orthotopically grafted mouse extensor digitorurn longus muscles (EDL) and fiber type diameter distribution in the graft was compared with control muscles. Histochemical fiber typing, based on myofibrillar ATPase reactions, indicated that type 1 fiber accounted for < 1%, type 2a fibers for 30%, and type 2b fibers for 69% of the total fiber population of the graft. In control muscles of 56‐day‐old and 156‐day‐old mice, type 1 fibers accounted for <1%, type 2a fibers for 36%, and type 2b fibers for 63% of the total fiber population of normal muscles. The regenerating myofibers in stabilized grafts failed to achieve the normal fiber diameter. The type 2b fibers exhibited greater growth inhibition than did type 2a fibers.